Synergic antibacterial activity of Guar gum functionalized 2D-MoS2-Gelatin-Ag nanocomposites

IF 4.4 3区化学 Q1 CHEMISTRY, INORGANIC & NUCLEAR

Inorganic Chemistry Communications Pub Date : 2025-03-08 DOI:10.1016/j.inoche.2025.114296

Y.K. Poojashree , Belagal Motatis Anil kumar , Karuppannan Suvetha , Aralakuppe N. Priyadarshini , Kalappa Prashantha , Honnappa Nagarajaiah , Muddenahalli S Sudhanva , Rangappa Shobith , Yarabahally R Girish

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Abstract

A novel nano composite, Guar-gum functionalized 2D-MoS₂-Ag, was synthesized through a facile green synthesis method with in situ UV light irradiation method using varying concentrations of silver nitrate. This environmentally friendly approach aimed to integrate silver nanoparticles into the MoS₂ matrix. The synthesized nanocomposites was characterized using several techniques Fourier transform infrared spectroscopy (FT-IR) confirmed functionalization, UV visible spectroscopy (UV–Vis) revealed optical properties, and Field emission scanning electron microscopy (FESEM), transmission electron microscopy (TEM) provide insights into its morphology. Powder X-ray diffraction (PXRD) confirmed the crystalline structure of the composites.

The antibacterial properties of synthesized nano composites was evaluated using the spread plate method against gram positive Staphylococcus Aureus (SA), Methicillin Resistant Staphylococcus Aureus (MRSA) and gram negative Escherichia Coli (E-Coli). The results demonstrated significant antibacterial activity, with decreased bacterial proliferation and colony forming abilities in concentration dependent manner. The enhanced performance was attributed to the synergistic effects of silver nanoparticles, which exhibit dual mechanisms by releasing silver ions and direct interaction with bacterial cell membranes. This study suggests that the Guar-gum functionalized 2D-MoS₂ (GG-Gel-MoS₂-Ag-1.0) is a promising antibacterial material with potential applications in medical and environmental fields.

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来源期刊

Inorganic Chemistry Communications 化学-无机化学与核化学

CiteScore

5.50

自引率

7.90%

发文量

1013

审稿时长

53 days

期刊介绍： Launched in January 1998, Inorganic Chemistry Communications is an international journal dedicated to the rapid publication of short communications in the major areas of inorganic, organometallic and supramolecular chemistry. Topics include synthetic and reaction chemistry, kinetics and mechanisms of reactions, bioinorganic chemistry, photochemistry and the use of metal and organometallic compounds in stoichiometric and catalytic synthesis or organic compounds.