Effect of bright light therapy on depression in patients with schizophrenia: A pilot study

IF 3.7 2区医学 Q1 PSYCHIATRY

Journal of psychiatric research Pub Date : 2025-03-09 DOI:10.1016/j.jpsychires.2025.02.050

Chia-Shin Guo , Doreen Phiri , Hsin-Chien Lee , Yen-Kuang Lin , Jimmy Alvin Metrado Kwa , Min-Huey Chung

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引用次数: 0

Abstract

Objective

In this pilot study, we investigated the effects of bright light therapy on depression in schizophrenia using a quasi-experimental design involving random assignment.

Methods

We included patients with schizophrenia who had stable psychiatric symptoms. Experimental group (n = 16) received light therapy while control group (n = 12) received only regular indoor light. The intervention was administered in the morning once a day for 50 min for three weeks. Scores of the Chinese version of the Calgary Depression Scale for Schizophrenia (CDSS-C), Chinese version of the Positive and Negative Syndrome Scale (PANSS-C), Clinical Global Impression-Schizophrenia Scale (CGI-SCH), and Stressful Life Event Scale (SLES) were measured at baseline (T0), immediately after 5th day of the intervention (T1), immediately after the 15th day of intervention (T2), and at the 14-day follow-up (T3). A generalized estimating equation (GEE) analysis was performed to analyse group × time interaction effects and effect of bright light therapy on depression.

Results

Results indicated that bright light therapy alleviated depressive symptoms in patients with schizophrenia after controlling for internal or surgical diseases and disease duration (in years). However, the effect was not maintained two weeks after the treatment.

Conclusion

These findings suggest that bright light therapy is a nonpharmacological adjunct treatment approach for patients with stable psychiatric symptoms.

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来源期刊

Journal of psychiatric research 医学-精神病学

CiteScore

7.30

自引率

2.10%

发文量

622

审稿时长

130 days

期刊介绍： Founded in 1961 to report on the latest work in psychiatry and cognate disciplines, the Journal of Psychiatric Research is dedicated to innovative and timely studies of four important areas of research: (1) clinical studies of all disciplines relating to psychiatric illness, as well as normal human behaviour, including biochemical, physiological, genetic, environmental, social, psychological and epidemiological factors; (2) basic studies pertaining to psychiatry in such fields as neuropsychopharmacology, neuroendocrinology, electrophysiology, genetics, experimental psychology and epidemiology; (3) the growing application of clinical laboratory techniques in psychiatry, including imagery and spectroscopy of the brain, molecular biology and computer sciences;