Near-infrared carbon dots: pioneering emerging frontiers in biomedical applications

IF 5.7 3区材料科学 Q2 Materials Science

New Carbon Materials Pub Date : 2025-02-01 DOI:10.1016/S1872-5805(25)60946-2

Qian HE , Yan-li YANG , Rui-jiao LI, Dan MA, Li-yun ZHANG

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Abstract

Carbon dots (CDs) are fluorescent carbon-based nanomaterials with sizes smaller than 10 nm, that are renowned for their exceptional properties, including superior antiphotobleaching, excellent biocompatibility, and minimal toxicity, which have received significant interest. Near-infrared (NIR) light has emerged as an ideal light source in the biological field due to its advantages of minimal scattering and absorption, long wavelength emission, increased tissue penetration, and reduced interference from biological backgrounds. CDs with efficient absorption and/or emission characteristics in the NIR spectrum have shown remarkable promise in the biomedical uses. This study provides a comprehensive overview of the preparation methods and wavelength modulation strategies for near-infrared CDs and reviews research progress in their use in the areas of biosensing, bioimaging, and therapy. It also discusses current challenges and clinical prospects, aimed at deepening our understanding of the subject and promoting further advances in this field.

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近红外碳点：开拓生物医学应用的新领域

碳点（cd）是尺寸小于10纳米的荧光碳基纳米材料，以其卓越的性能而闻名，包括卓越的抗光漂白，优异的生物相容性和最小的毒性，已经引起了人们的极大兴趣。近红外光具有散射吸收小、波长发射长、组织穿透能力强、生物背景干扰小等优点，已成为生物领域的理想光源。在近红外光谱中具有高效吸收和/或发射特性的CDs在生物医学应用中显示出显着的前景。本文综述了近红外CDs的制备方法和波长调制策略，并综述了近红外CDs在生物传感、生物成像和治疗等领域的研究进展。它还讨论了当前的挑战和临床前景，旨在加深我们对该主题的理解并促进该领域的进一步发展。下载：下载高分辨率图片（53KB）下载：下载全尺寸图片

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来源期刊

New Carbon Materials MATERIALS SCIENCE, MULTIDISCIPLINARY-

CiteScore

6.10

自引率

8.80%

发文量

3245

审稿时长

5.5 months

期刊介绍： New Carbon Materials is a scholarly journal that publishes original research papers focusing on the physics, chemistry, and technology of organic substances that serve as precursors for creating carbonaceous solids with aromatic or tetrahedral bonding. The scope of materials covered by the journal extends from diamond and graphite to a variety of forms including chars, semicokes, mesophase substances, carbons, carbon fibers, carbynes, fullerenes, and carbon nanotubes. The journal's objective is to showcase the latest research findings and advancements in the areas of formation, structure, properties, behaviors, and technological applications of carbon materials. Additionally, the journal includes papers on the secondary production of new carbon and composite materials, such as carbon-carbon composites, derived from the aforementioned carbons. Research papers on organic substances will be considered for publication only if they have a direct relevance to the resulting carbon materials.