Corazón, amiodarona y glándula tiroides: la tormenta perfecta. A propósito de un caso

Abstract

Thyroid storm is an endocrine emergency that can lead to multiorgan dysfunction and death. Its etiology may vary, but when induced by amiodarone, it poses challenges in both diagnosis and clinical management. The relationship between amiodarone and thyroid function can cause hypothyroidism in up to 25% of cases and hyperthyroidism in up to 10% of cases. The case of a 68-year-old woman who presented with refractory atrial fibrillation to amiodarone treatment, subsequently developing an amiodarone-induced thyroid storm, is described. Despite conventional first-line antiarrhythmic management, she experienced cardiogenic shock and multiorgan failure. Following antithyroid therapy implementation, the patient exhibited a notable clinical improvement and progressive stabilization. The challenges in the diagnosis and management of this patient are discussed.