An International Perspective on Priority Areas for Women’s Cardiovascular Health Research: Qualitative Findings From a Cross-Sectional Survey

Abstract

Background

The Global Cardiovascular Research Funders Forum (GCRFF) unites international research funders interested in supporting cardiovascular disease (CVD) research. One focus area is women’s cardiovascular health; the present study aimed to identify priority themes for future joint research funding opportunities.

Methods

After ethics approval, a survey was developed based on literature review, GCRFF feedback, and input from methodologists/content experts. The survey comprised 3 open-ended and 5 multiple-choice questions. With the use of widespread dissemination strategies, an electronic survey portal was opened for 8 weeks, from November 15, 2023, to January 15, 2024, with various language options. Results were downloaded into a secure REDCap database for analysis. Independent theming of responses was completed by 3 reviewers until coding consensus was achieved, following which 1 coder completed the remaining theming. Descriptive statistics are reported.

Results

Among the 191 responses, all 9 GCRFF countries were represented. Most respondents identified as women (74%) and clinicians/academics (77%); fewer people with lived or living experience participated (23%). Common themes included women-specific risk factors and prevention strategies (56%), life-course issues (43%), and sex- and gender-specific treatments and outcomes (36%). Common topics were CVD (66%), coronary artery disease (CAD) (18%), and heart disease (13%). Designated research pillars included clinical (52%), population health (36%), and basic science (30%). Solutions proposed included knowledge generation (71%), increased funding (55%), networking researchers (52%), and knowledge mobilisation (41%). Congruence of priority ordering was demonstrated between sex and respondent residence subgroups.

Conclusion

Diverse international input prioritised research in risk factors and prevention strategies specific to women and in sex- and gender-specific treatment and outcomes of heart disease, with considerations of life-course issues across all research pillars.