Diagnostics, reconstructive approaches, and outcomes in female urethroplasty patients

IF 3.7 2区医学 Q1 UROLOGY & NEPHROLOGY

BJU International Pub Date : 2025-03-13 DOI:10.1111/bju.16701

Marjan Waterloos, Nicolaas Lumen, Jeremy L. Ockrim, Marco Falcone, Osman Kose, Ofer Z. Shenfeld, Malte W. Vetterlein, Tamsin J. Greenwell, from the European Association of Urology Section of Genitourinary Reconstructive Surgeons Female Reconstruction Group

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引用次数: 0

Abstract

Objectives

To gain further understanding of current outcomes regarding urethroplasty for female urethral stricture disease.

Methods

The European Association of Urology Section of Genitourinary Reconstructive Surgeons formed the Female Reconstruction Group to enhance multicentric collaboration, and to generate more evidence on the most effective treatment options for female patients with recurrent urethral stricture. Patients were eligible for inclusion if they had a urethral stricture and had undergone one of three reconstructive procedures, namely ventral onlay flap (VOFU), ventral onlay graft (VOGU) or dorsal onlay graft (DOGU) urethroplasty. Outcomes of specific interest were stricture-free survival and prognostic factors.

Results

Of a total of 165 included patients, the surgical techniques were VOFU, VOGU, DOGU in 17, 115 and 33 patients, respectively. The median follow-up was 29 months. The 2-year stricture-free survival rate was 73%, 86% and 80% in respectively the VOFU, VOGU and DOGU groups, with no significant difference between the groups. Prior radiotherapy (P = 0.015) was identified as an independent predictor for stricture recurrence.

Conclusion

Female urethroplasty is a safe treatment option with excellent patency rates. Mid-term stricture-free survival rate after different types of urethroplasty is encouraging in females.

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女性尿道成形术患者的诊断、重建方法和结果

目的：进一步了解女性尿道狭窄疾病尿道成形术的现状。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

BJU International 医学-泌尿学与肾脏学

CiteScore

9.10

自引率

4.40%

发文量

262

审稿时长

1 months

期刊介绍： BJUI is one of the most highly respected medical journals in the world, with a truly international range of published papers and appeal. Every issue gives invaluable practical information in the form of original articles, reviews, comments, surgical education articles, and translational science articles in the field of urology. BJUI employs topical sections, and is in full colour, making it easier to browse or search for something specific.