GSTA2 mitigates DEHP-induced reproductive toxic effects

IF 12.1 1区医学 Q1 UROLOGY & NEPHROLOGY

Nature Reviews Urology Pub Date : 2025-03-12 DOI:10.1038/s41585-025-01016-8

Maria Chiara Masone

引用次数: 0

Abstract

The environmental pollutant bis(2-ethylhexyl) phthalate (DEHP) induces oxidative stress, leading to impaired sperm parameters and reproductive toxicity.

In a new study published in Molecular and Cellular Endocrinology, the role of glutathione S-transferase A2 (GSTA2) — a known detoxifying agent against environmental pollutants — was assessed in counteracting DEHP-induced reproductive damage.

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来源期刊

Nature Reviews Urology 医学-泌尿学与肾脏学

CiteScore

12.50

自引率

2.60%

发文量

123

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Urology is part of the Nature Reviews portfolio of journals.Nature Reviews' basic, translational and clinical content is written by internationally renowned basic and clinical academics and researchers. This journal targeted readers in the biological and medical sciences, from the postgraduate level upwards, aiming to be accessible to professionals in any biological or medical discipline. The journal features authoritative In-depth Reviews providing up-to-date information on topics within a field's history and development. Perspectives, News & Views articles, and the Research Highlights section offer topical discussions and opinions, filtering primary research from various medical journals. Covering a wide range of subjects, including andrology, urologic oncology, and imaging, Nature Reviews provides valuable insights for practitioners, researchers, and academics within urology and related fields.