Initial insights into post-contrast enhancement in ultra-low-field MRI: Case Report.

Frontiers in neuroimaging Pub Date : 2025-02-25 eCollection Date: 2025-01-01 DOI:10.3389/fnimg.2025.1507522
Ahmed Altaf, Muhammad Sami Alam, Sibgha Khan, Ali Azan, Fatima Mubarak, Edmond Knopp, Khan Siddiqui, Syed Ather Enam
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Abstract

Brain tumors represent a significant burden, particularly in low- and middle-income countries (LMICs) where access to neuroimaging techniques is often limited. Conventional MRI machines are expensive and bulky, posing a significant challenge in the diagnosis and treatment of brain tumors in LMICs. However, an emerging technology, ultra-low field magnetic resonance imaging (pULF-MRI), has the potential to address this limitation. This study aimed to evaluate the feasibility and effectiveness of post-contrast enhancement in a pULF-MRI scanner for brain tumor imaging in LMICs. A single case study was conducted, and post-contrast enhancement was successfully achieved, revealing the presence of a tumor which was subsequently confirmed on biopsy. To our knowledge, this is the first study to demonstrate the feasibility of post-contrast enhancement in a pULF-MRI scanner for brain tumor imaging. This technology has the potential to significantly improve access to neuroimaging in LMICs, leading to earlier diagnosis and more effective treatment of brain tumors. These promising results suggest that further studies are warranted to explore the potential of pULF-MRI for large-scale screening and diagnosis of brain tumors in LMICs. This can provide a future roadmap for neuroimaging in LMICs, providing a cost-effective and accessible way to diagnose and treat brain tumors, leading to improved healthcare outcomes with a further prospective clinical trial.

超低场MRI造影后增强的初步见解:病例报告。
脑肿瘤是一个重大负担,特别是在获得神经成像技术往往有限的低收入和中等收入国家。传统的核磁共振成像仪价格昂贵且体积庞大,这对低收入国家脑肿瘤的诊断和治疗构成了重大挑战。然而,一项新兴技术,超低场磁共振成像(pULF-MRI),有可能解决这一限制。本研究旨在评估pULF-MRI扫描仪对比后增强用于低收入国家脑肿瘤成像的可行性和有效性。我们进行了一个单独的病例研究,并成功地实现了对比增强,显示了肿瘤的存在,随后在活检中证实了肿瘤的存在。据我们所知,这是第一个证明在pULF-MRI扫描仪中进行脑肿瘤成像的对比后增强可行性的研究。这项技术有可能显著改善中低收入国家获得神经影像学的机会,从而导致脑肿瘤的早期诊断和更有效的治疗。这些令人鼓舞的结果表明,有必要进一步研究pULF-MRI在低收入国家大规模筛查和诊断脑肿瘤方面的潜力。这可以为中低收入国家的神经成像提供未来的路线图,提供一种具有成本效益和可获得的方法来诊断和治疗脑肿瘤,从而通过进一步的前瞻性临床试验改善医疗保健结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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