{"title":"Impact of COVID-19 pandemic on influenza vaccination rates among healthcare workers and the general population in Saudi Arabia: A meta-analysis.","authors":"Salah Alshagrawi, Ahmed Hazazi","doi":"10.1080/21645515.2025.2477954","DOIUrl":null,"url":null,"abstract":"<p><p>We aim to identify how the seasonal IVRs have been impacted by the COVID-19 pandemic in Saudi Arabia. We conducted a meta-analysis of cross-sectional studies to statistically examine IVRs before and after the COVID-19 pandemic among the general population and HCWs in Saudi Arabia. The meta-regression analysis showed a significant correlation among the general population was observed between the IVR and the timing of the study, with a mean effect size estimate of 14.3 (95% CI = 5.7-22.9; <i>p</i> < .001). Among HCWs, no significant relationship was observed between the IVR and the timing of the study, with a mean effect size estimate of 6.7 (95% CI = -19.3-32.7; <i>p</i> = .5). COVID-19 might have contributed to a rise in IVR among HCWs, whereas the general population has seen a decline in IVR.</p>","PeriodicalId":49067,"journal":{"name":"Human Vaccines & Immunotherapeutics","volume":"21 1","pages":"2477954"},"PeriodicalIF":4.1000,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11901379/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Human Vaccines & Immunotherapeutics","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/21645515.2025.2477954","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/3/11 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"BIOTECHNOLOGY & APPLIED MICROBIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
We aim to identify how the seasonal IVRs have been impacted by the COVID-19 pandemic in Saudi Arabia. We conducted a meta-analysis of cross-sectional studies to statistically examine IVRs before and after the COVID-19 pandemic among the general population and HCWs in Saudi Arabia. The meta-regression analysis showed a significant correlation among the general population was observed between the IVR and the timing of the study, with a mean effect size estimate of 14.3 (95% CI = 5.7-22.9; p < .001). Among HCWs, no significant relationship was observed between the IVR and the timing of the study, with a mean effect size estimate of 6.7 (95% CI = -19.3-32.7; p = .5). COVID-19 might have contributed to a rise in IVR among HCWs, whereas the general population has seen a decline in IVR.
期刊介绍：
(formerly Human Vaccines; issn 1554-8619)
Vaccine research and development is extending its reach beyond the prevention of bacterial or viral diseases. There are experimental vaccines for immunotherapeutic purposes and for applications outside of infectious diseases, in diverse fields such as cancer, autoimmunity, allergy, Alzheimer’s and addiction. Many of these vaccines and immunotherapeutics should become available in the next two decades, with consequent benefit for human health. Continued advancement in this field will benefit from a forum that can (A) help to promote interest by keeping investigators updated, and (B) enable an exchange of ideas regarding the latest progress in the many topics pertaining to vaccines and immunotherapeutics.
Human Vaccines & Immunotherapeutics provides such a forum. It is published monthly in a format that is accessible to a wide international audience in the academic, industrial and public sectors.
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