Comparison Between Etorphine-Xylazine with or Without Butorphanol and Butorphanol-Azaperone-Medetomidine For the Anesthesia of Free-Ranging Musk Ox (Ovibos moschatus).
Benjamin Lamglait, Laura Van Driessche, Marion Jalenques, Vincent Brodeur, Joëlle Taillon, Pauline Delnatte, Steeve D Côté, Stéphane Lair
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引用次数: 0
Abstract
Historically, free-ranging musk oxen (Ovibos moschatus) were anesthetized with potent opioids such as etorphine, which are often associated with marked respiratory depression. The goal of this study was to investigate alternatives to the etorphine-xylazine combination (EtXy) traditionally used in this species. First, the potential benefit of postinduction butorphanol administrations to musk oxen anesthetized with EtXy was assessed. Then, the use of butorphanol-azaperone-medetomidine (BAM-II) as an alternative to the use of potent opioids for the immobilization of free-ranging musk oxen was evaluated. Eighty-nine musk oxen were ground darted with either a combination of EtXy (n = 52) or BAM-II (n = 37), and 10 animals from the EtXy group received an IM injection of butorphanol at 1 mg/mg of etorphine (EtXyB). Intranasal oxygen (1 L/100 kg per minute) was administered to all animals. Respiratory rate, heart rate, peripheral capillary oxygen saturation (SpO2), end-tidal carbon dioxide (EtCO2), and rectal temperature were compared between groups. Postinduction butorphanol injection was associated with a decrease in heart rate (P = 0.001) and increases in respiratory rate (P < 0.001), rectal temperature (P < 0.001) and SpO2 (P < 0.001), but did not affect EtCO2 (P = 0.069). Musk oxen anesthetized with BAM-II had a significantly lower EtCO2 (P = 0.009) and heart rate (P = 0.009) compared with musk oxen anesthetized with EtXy or EtXyB, and a higher SpO2 compared with animals anesthetized with EtXy (P < 0.001). There was no significant difference between induction (P = 0.98) or recovery (P = 0.74) time for the three protocols used. This study provides evidence that postinduction butorphanol administration added to the etorphine-xylazine protocol can decrease respiratory depression. Additionally, BAM-II can be used as an affective drug combination to immobilize musk oxen in their natural environment.
期刊介绍：
The Journal of Zoo and Wildlife Medicine (JZWM) is considered one of the major sources of information on the biology and veterinary aspects in the field. It stems from the founding premise of AAZV to share zoo animal medicine experiences. The Journal evolved from the long history of members producing case reports and the increased publication of free-ranging wildlife papers.
The Journal accepts manuscripts of original research findings, case reports in the field of veterinary medicine dealing with captive and free-ranging wild animals, brief communications regarding clinical or research observations that may warrant publication. It also publishes and encourages submission of relevant editorials, reviews, special reports, clinical challenges, abstracts of selected articles and book reviews. The Journal is published quarterly, is peer reviewed, is indexed by the major abstracting services, and is international in scope and distribution.
Areas of interest include clinical medicine, surgery, anatomy, radiology, physiology, reproduction, nutrition, parasitology, microbiology, immunology, pathology (including infectious diseases and clinical pathology), toxicology, pharmacology, and epidemiology.
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