Clinical Outcomes of a Refractive Extended Depth of Focus Intraocular Lens.

Abstract

Purpose: To evaluate the clinical and patient-reported outcomes of the toric version of a refractive extended depth of focus intraocular lens (IOL).

Methods: This was a prospective observational study including 26 eyes of 26 patients (age range: 58 to 88 years) who underwent cataract surgery with implantation of the LuxSmart toric IOL (Bausch & Lomb GmbH). Changes in distance, intermediate (80 cm), and near (40 cm) visual acuities, manifest refraction, defocus curve, distance photopic contrast sensitivity (CSV-1000 test), and patient-reported outcomes (Catquest-9SF questionnaire) were evaluated during a 3-month follow-up.

Results: Mean 3-month postoperative uncorrected distance, corrected distance, distance-corrected intermediate, and distance-corrected near visual acuities of 0.10 ± 0.11, 0.03 ± 0.08, 0.06 ± 0.13, and 0.38 ± 0.22 logarithm of the minimum angle of resolution (logMAR) were found, respectively. Uncorrected and corrected distance visual acuity improved significantly with surgery (P < .001). In the defocus curve, mean visual acuity was 0.30 logMAR or better for defocus between +0.50 and -2.00 D, without significant changes during the follow-up (P ⩾ .071). The postoperative spherical equivalent was within ±0.50 and ±1.00 diopters (D) in 92% and 96% of eyes, respectively. Surgically induced astigmatism prediction error ranged between -0.37 and 0.80 D, with a mean value of 0.11 ± 0.28 D. Mean 3-month postoperative contrast sensitivity was within or close to the upper limit of the normality range for most spatial frequencies. Mean 3-month postoperative overall Rasch calibrated Catquest score was -1.68 ± 1.04, with 96.2% of patients satisfied with the vision achieved. IOL rotations of 5º or less were observed in 92.3% of eyes.

Conclusions: The toric extended depth of focus IOL evaluated provides a good distance and intermediate functional vision in eyes with preexisting corneal astigmatism, with functional near visual performance for most patients. [J Refract Surg. 2025;41(3):e238-e247.].