Dr. Jagadeesh Krishnan, Mr. Kaja Sahib, Ms. Keerthana G. Nair, Mr. Arshad Jouhar T, Dr. Rony Rajan Paul
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引用次数: 0
Abstract
Organofluorine compounds are of pivotal significance particularly, in drug and agrochemical industries and different strategies have been designed for their synthesis. The last two decades witnessed the emergence of difluorocarbene as an efficient synthetic tool, providing easy access to organofluorine compounds. This review summarises the reactions of difluorocarbene generated from Ruppert-Prakash reagent (TMSCF3) and its derivatives TMSCF2Cl and TMSCF2Br. Among the various fluorination techniques available, the difluorocarbene chemistry offers a cost effective and easy procedure, opening avenue to a large number of organofluorine compounds. This review details the developments in the utility of difluorocarbene generated from TMSCF3 and its derivatives, till date.
期刊介绍：
The Chemical Record (TCR) is a "highlights" journal publishing timely and critical overviews of new developments at the cutting edge of chemistry of interest to a wide audience of chemists (2013 journal impact factor: 5.577). The scope of published reviews includes all areas related to physical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, polymer chemistry, materials chemistry, bioorganic chemistry, biochemistry, biotechnology and medicinal chemistry as well as interdisciplinary fields.
TCR provides carefully selected highlight papers by leading researchers that introduce the author''s own experimental and theoretical results in a framework designed to establish perspectives with earlier and contemporary work and provide a critical review of the present state of the subject. The articles are intended to present concise evaluations of current trends in chemistry research to help chemists gain useful insights into fields outside their specialization and provide experts with summaries of recent key developments.
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