RETRACTION: Downregulation of SDCBP Inhibits Cell Proliferation and Induces Apoptosis by Regulating PI3K/AKT/mTOR Pathway in Gastric Carcinoma

IF 3.2 4区 生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY
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引用次数: 0

Abstract

RETRACTION: B. Qian, Z. Yao, Y. Yang, N. Li, and Q. Wang, “Downregulation of SDCBP Inhibits Cell Proliferation and Induces Apoptosis by Regulating PI3K/AKT/mTOR Pathway in Gastric Carcinoma,” Biotechnology and Applied Biochemistry 69, no. 1 (2022): 240–247, https://doi.org/10.1002/bab.2103.

The above article, published online on 1 January 2021 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal Editor-in-Chief, Kaiming Ye; the International Union of Biochemistry and Molecular Biology; and John Wiley & Sons. The retraction has been agreed due to concerns raised by third parties. Specifically, the article reports experiments in a non-verifiable cell line, BGC-803. Further investigation by the publisher has found that the article has been accepted solely based on the compromised peer review. Parts of the experimental methods in this manuscript lack sufficient detail to interpret and reproduce the findings. Additionally, the following cell lines mentioned and/or used in this study were found to be problematic/contaminated: BGC-823 [1, 2], MKN-28 [3] and SGC-7901 [1, 2]. Accordingly, the conclusions of this article are considered invalid by the editors and the article must be retracted. The authors were contacted but did not respond regarding the decision to retract.

结论:胃癌中SDCBP下调通过调控PI3K/AKT/mTOR通路抑制细胞增殖,诱导细胞凋亡。
引用本文:钱波,姚志强,杨艳,李宁,王琪,“SDCBP在胃癌组织中表达的调控PI3K/AKT/mTOR通路抑制细胞增殖和诱导细胞凋亡的作用”,《生物技术与应用生物化学》,第69期,no。上述文章于2021年1月1日在Wiley online Library (wileyonlinelibrary.com)上发表,经主编叶凯明同意撤回;国际生物化学与分子生物学联合会;约翰·威利&;儿子。由于第三方的担忧,双方同意撤回声明。具体来说,这篇文章报道了一种不可验证的细胞系BGC-803的实验。出版商的进一步调查发现,这篇文章完全是基于折衷的同行评议而被接受的。本手稿中部分实验方法缺乏足够的细节来解释和重现研究结果。此外,本研究中提到和/或使用的以下细胞系被发现有问题/受到污染:BGC-823 [1,2], MKN-28[3]和SGC-7901[1,2]。因此,编辑认为这篇文章的结论无效,文章必须撤回。我们联系了作者,但没有就撤回决定作出回应。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Biotechnology and applied biochemistry
Biotechnology and applied biochemistry 工程技术-生化与分子生物学
CiteScore
6.00
自引率
7.10%
发文量
117
审稿时长
3 months
期刊介绍: Published since 1979, Biotechnology and Applied Biochemistry is dedicated to the rapid publication of high quality, significant research at the interface between life sciences and their technological exploitation. The Editors will consider papers for publication based on their novelty and impact as well as their contribution to the advancement of medical biotechnology and industrial biotechnology, covering cutting-edge research in synthetic biology, systems biology, metabolic engineering, bioengineering, biomaterials, biosensing, and nano-biotechnology.
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