Association of Aortic Root and Valve Morphology With De Novo Aortic Valve Regurgitation After Implantation of Left Ventricular Assist Device.

IF 2.2 3区医学 Q3 ENGINEERING, BIOMEDICAL

Artificial organs Pub Date : 2025-03-12 DOI:10.1111/aor.14987

Takashi Murakami, Yusuke Misumi, Daisuke Yoshioka, Takuji Kawamura, Ai Kawamura, Shin Yajima, Shunsuke Saito, Takashi Yamauchi, Shigeru Miyagawa

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引用次数: 0

Abstract

Background: The development of aortic valve regurgitation (AR) negatively affects the survival of patients with continuous-flow left ventricular assist device (LVAD) support. Although several risk factors have been identified, little is known about the effect of preoperative aortic root and valve morphology on the development of de novo AR after LVAD implantation.

Methods: Between April 2018 and September 2023, 87 patients underwent durable LVAD implantation at our department. Of these, the 15 eligible patients who underwent preoperative electrocardiography-synchronized cardiac contrast-enhanced computed tomography were included in this study. Baseline aortic root and valve morphology and its relationship with the postoperative development of AR were retrospectively reviewed.

Results: The mean duration of LVAD support was 1208 ± 618 days. At 60 months postsurgery, 10 patients had mild or greater AR (Group I) and the others did not (Group N). The measurement of baseline aortic root morphology showed that the ratio of virtual basal ring diameter to geometric height (VBD/GH) was significantly larger for Group I (1.70 ± 0.024 vs. 1.48 ± 0.034; p = 0.0001).

Conclusions: A large preoperative VBD/GH is a significant risk factor for de novo AR. This finding may assist in determining the surgical indications for concomitant aortic valve procedures with durable LVAD implantation.

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来源期刊

Artificial organs 工程技术-工程：生物医学

CiteScore

4.30

自引率

12.50%

发文量

303

审稿时长

4-8 weeks

期刊介绍： Artificial Organs is the official peer reviewed journal of The International Federation for Artificial Organs (Members of the Federation are: The American Society for Artificial Internal Organs, The European Society for Artificial Organs, and The Japanese Society for Artificial Organs), The International Faculty for Artificial Organs, the International Society for Rotary Blood Pumps, The International Society for Pediatric Mechanical Cardiopulmonary Support, and the Vienna International Workshop on Functional Electrical Stimulation. Artificial Organs publishes original research articles dealing with developments in artificial organs applications and treatment modalities and their clinical applications worldwide. Membership in the Societies listed above is not a prerequisite for publication. Articles are published without charge to the author except for color figures and excess page charges as noted.