Use of Safety Net Enclosures as an Additional Treatment of Neuropsychiatric Symptoms in Dementia: A Prospective Cohort Study.

IF 1.8 4区医学 Q3 CLINICAL NEUROLOGY

Alzheimer Disease & Associated Disorders Pub Date : 2025-03-14 DOI:10.1097/WAD.0000000000000666

Katinka Hummelen, Charlotte Schrama, Rob Kok

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引用次数: 0

Abstract

Objective: Safety net enclosures are used in addition to (non-) pharmacological interventions in patients suffering from neuropsychiatric symptoms in dementia. However, no data on effectiveness are available.

Methods: In a prospective observational cohort study of 81 patients diagnosed with dementia, and admitted to a geriatric ward of a psychiatric hospital, available behavioral assessment scores were used to compare 45 patients who used safety net enclosures with 36 patients who never used safety net enclosures. Behavior was evaluated weekly using the Cohen-Mansfield Agitation Inventory (CMAI) and the Neuropsychiatric Inventory Questionnaire (NPI-Q) at admission, start of the enclosure, and before discharge.

Results: At baseline, the intervention group had a significantly higher CMAI and NPI-Q-score. At follow-up, the intervention group showed a greater improvement in CMAI [median -13.0 (interquartile range: -27.3 to 0.05) vs 0.0 (interquartile range: -6.0 to 2.5); Mann-Whitney U = 338.5 ( P = 0.005)] compared with the comparison group. Only some NPI-Q subscales showed significantly greater improvement during the intervention than in the comparison group.

Conclusions: Our observational study is the first to present effectiveness data on Neuropsychiatric symptoms in persons suffering from dementia and suggests significantly greater improvement in CMAI scores when using safety net enclosures. However, almost no significant differences were found in other outcomes.

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使用安全网围栏作为痴呆患者神经精神症状的额外治疗：一项前瞻性队列研究

目的：除了（非）药物干预外，安全网围栏还用于患有痴呆神经精神症状的患者。然而，没有关于有效性的数据。方法：在一项前瞻性观察队列研究中，81名被诊断为痴呆并住进精神病院老年病房的患者，使用现有的行为评估评分来比较45名使用安全网围栏的患者和36名从未使用安全网围栏的患者。在入院、围护开始和出院前，每周使用Cohen-Mansfield躁动量表（CMAI）和神经精神量表问卷（NPI-Q）对行为进行评估。结果：在基线时，干预组的CMAI和npi - q得分显著高于对照组。随访时，干预组CMAI改善更大[中位数-13.0（四分位数范围：-27.3至0.05）vs . 0.0（四分位数范围：-6.0至2.5）；Mann-Whitney U = 338.5 (P = 0.005)]与对照组比较。只有一些NPI-Q量表在干预期间比对照组有明显改善。结论：我们的观察性研究首次提供了痴呆症患者神经精神症状的有效性数据，并表明使用安全网围篱可显著提高CMAI评分。然而，在其他结果上几乎没有发现显著差异。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Alzheimer Disease & Associated Disorders 医学-病理学

CiteScore

3.10

自引率

4.80%

发文量

期刊介绍： Alzheimer Disease & Associated Disorders is a peer-reviewed, multidisciplinary journal directed to an audience of clinicians and researchers, with primary emphasis on Alzheimer disease and associated disorders. The journal publishes original articles emphasizing research in humans including epidemiologic studies, clinical trials and experimental studies, studies of diagnosis and biomarkers, as well as research on the health of persons with dementia and their caregivers. The scientific portion of the journal is augmented by reviews of the current literature, concepts, conjectures, and hypotheses in dementia, brief reports, and letters to the editor.