Mental Health Challenges in Cancer Survivors From Diverse Backgrounds During COVID-19 Pandemic: Insights From the All of Us Research Program.

IF 3.3 2区医学 Q2 ONCOLOGY

Psycho‐Oncology Pub Date : 2025-03-01 DOI:10.1002/pon.70119

Zhiyu Qian, Mansoo Cho, Kevin Zhangxu, Faith Morley, Henry K Onyeaka, Daniel R Stelzl, Filippo Dagnino, Hanna Zurl, Stephan M Korn, Alexander P Cole, Hermioni L Amonoo, Kevin H Kensler, Quoc-Dien Trinh

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引用次数: 0

Abstract

Background: The COVID-19 pandemic exacerbated mental health challenges. This study aimed to investigate the mental health impact of the pandemic on cancer survivors from diverse backgrounds using the All of Us Research Program's COVID-19 Participant Experience (COPE) survey.

Methods: This analysis included respondents of the COPE survey with average depression, anxiety, and self-harm metrics computed for individuals completing multiple survey iterations. Multivariable logistic regression assessed the relationship between cancer survivorship, demographic factors, and mental health outcomes. Sensitivity analyses were conducted to investigate peak mental health challenges and time trend.

Results: Among 100,203 respondents, 20,561 (20.5%) were cancer survivors. Cancer survivors differed demographically from the general population, tending to be older and more likely to report higher socioeconomic status. Cancer survivors exhibited significantly higher odds of self-harm (aOR = 1.09, 95% CI 1.01-1.18). Sensitivity analyses focusing on peak mental health scores revealed that cancer survivors had significantly increased odds of experiencing anxiety (aOR = 1.11, 95% CI 1.06-1.17), depression (aOR = 1.11, 95% CI 1.06-1.17), and self-harm tendencies (aOR = 1.09, 95% CI 1.01-1.18) compared to non-cancer survivors. Within the cancer survivor subgroup, younger age, gender and sexual minority status, lower income, and widowed/separated/divorced status were associated with worse mental health outcomes.

Conclusion: During the COVID-19 pandemic, cancer survivors exhibited significantly higher odds of depression, anxiety, and self-harm compared to non-survivors, with certain subgroups demonstrating heightened vulnerability. Our study highlights the critical need for integrated mental health services in cancer survivorship care programs, especially among those from underserved groups who are at high risk, as we continue to evolve with the pandemic.

查看原文本刊更多论文

2019冠状病毒病大流行期间不同背景的癌症幸存者面临的心理健康挑战：来自我们所有人研究项目的见解。

背景：2019冠状病毒病大流行加剧了心理健康挑战。本研究旨在通过我们所有人研究计划的COVID-19参与者体验（COPE）调查，调查大流行对来自不同背景的癌症幸存者的心理健康影响。方法：本分析纳入了COPE调查的应答者，并计算了完成多次调查迭代的个体的平均抑郁、焦虑和自残指标。多变量逻辑回归评估了癌症存活率、人口统计学因素和心理健康结果之间的关系。对心理健康高峰挑战和时间趋势进行敏感性分析。结果：100,203名受访者中，20,561名（20.5%）是癌症幸存者。癌症幸存者在人口统计学上与一般人群不同，他们往往年龄较大，更有可能报告较高的社会经济地位。癌症幸存者表现出更高的自残几率（aOR = 1.09, 95% CI 1.01-1.18）。关注心理健康评分峰值的敏感性分析显示，与非癌症幸存者相比，癌症幸存者经历焦虑（aOR = 1.11, 95% CI 1.06-1.17）、抑郁（aOR = 1.11, 95% CI 1.06-1.17）和自残倾向（aOR = 1.09, 95% CI 1.01-1.18）的几率显著增加。在癌症幸存者亚组中，年龄较小、性别和性少数、收入较低、丧偶/分居/离婚状态与较差的心理健康结果相关。结论：在2019冠状病毒病大流行期间，与非幸存者相比，癌症幸存者表现出明显更高的抑郁、焦虑和自残几率，某些亚组表现出更高的脆弱性。我们的研究强调了在癌症幸存者护理项目中提供综合心理健康服务的迫切需要，特别是那些来自服务不足的高风险群体的人，因为我们继续随着流行病的发展而发展。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Psycho‐Oncology 医学-心理学

CiteScore

6.30

自引率

8.30%

发文量

220

审稿时长

3-8 weeks

期刊介绍： Psycho-Oncology is concerned with the psychological, social, behavioral, and ethical aspects of cancer. This subspeciality addresses the two major psychological dimensions of cancer: the psychological responses of patients to cancer at all stages of the disease, and that of their families and caretakers; and the psychological, behavioral and social factors that may influence the disease process. Psycho-oncology is an area of multi-disciplinary interest and has boundaries with the major specialities in oncology: the clinical disciplines (surgery, medicine, pediatrics, radiotherapy), epidemiology, immunology, endocrinology, biology, pathology, bioethics, palliative care, rehabilitation medicine, clinical trials research and decision making, as well as psychiatry and psychology. This international journal is published twelve times a year and will consider contributions to research of clinical and theoretical interest. Topics covered are wide-ranging and relate to the psychosocial aspects of cancer and AIDS-related tumors, including: epidemiology, quality of life, palliative and supportive care, psychiatry, psychology, sociology, social work, nursing and educational issues. Special reviews are offered from time to time. There is a section reviewing recently published books. A society news section is available for the dissemination of information relating to meetings, conferences and other society-related topics. Summary proceedings of important national and international symposia falling within the aims of the journal are presented.