{"title":"Dosimetric comparison of three different cardiac CT angiography techniques in a dual-source scanner using size-specific dose estimation (SSDE)","authors":"Mostafa Robatjazi , Navid Sarmast Alizadeh , Mikaeil Molazadeh , Fatemeh Shokoohy , Seyed Alireza Javadinia , Amir Dareyni , Maryam Mosavi","doi":"10.1016/j.radphyschem.2025.112678","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>Cardiac computed tomography angiography (CCTA) is a non-invasive imaging technique for detecting coronary artery disease. This study aimed to evaluate radiation doses in three CCTA techniques using a dual-source CT scanner, focusing on Size-Specific Dose Estimation (SSDE) and other dose indexes.</div></div><div><h3>Methods</h3><div>Ninety-three patients were categorized into three groups: FLASH technique (44 patients), retrospective electrocardiogram (ECG) triggering technique (13 patients), and prospective ECG triggering technique (36 patients). Dose-length product (DLP), Volumetric CT dose index (CTDIvol), SSDE, and effective dose were calculated and compared among the groups.</div></div><div><h3>Results</h3><div>There was a significant difference in CTDIvol and DLP values (P < 0.001) among CCTA techniques. The retrospective technique had higher geometrical SSDE (gSSDE) and water-equivalent SSDE (wSSDE) values (P < 0.001), while the FLASH technique had lower values. No significant effective dose difference existed between prospective and FLASH techniques (P = 0.17), but significant differences were observed between FLASH vs. retrospective and prospective vs. retrospective (both P < 0.001). Gender did not significantly affect dose values. Correlation analysis showed poor correlations between gSSDE, wSSDE, related effective diameters, and factors like age, kV, and mAs.</div></div><div><h3>Conclusion</h3><div>This study highlights the importance of radiation dose consideration in selecting appropriate CCTA technique based on patient factors. The results showed that FLASH has the lowest doses, and incorporating SSDE improves dose accuracy. Our findings support the adoption of SSDE to optimize imaging protocols and enhance patient safety in cardiovascular imaging.</div></div>","PeriodicalId":20861,"journal":{"name":"Radiation Physics and Chemistry","volume":"232 ","pages":"Article 112678"},"PeriodicalIF":2.8000,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Radiation Physics and Chemistry","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0969806X25001707","RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, PHYSICAL","Score":null,"Total":0}
引用次数: 0
Abstract
Background
Cardiac computed tomography angiography (CCTA) is a non-invasive imaging technique for detecting coronary artery disease. This study aimed to evaluate radiation doses in three CCTA techniques using a dual-source CT scanner, focusing on Size-Specific Dose Estimation (SSDE) and other dose indexes.
Methods
Ninety-three patients were categorized into three groups: FLASH technique (44 patients), retrospective electrocardiogram (ECG) triggering technique (13 patients), and prospective ECG triggering technique (36 patients). Dose-length product (DLP), Volumetric CT dose index (CTDIvol), SSDE, and effective dose were calculated and compared among the groups.
Results
There was a significant difference in CTDIvol and DLP values (P < 0.001) among CCTA techniques. The retrospective technique had higher geometrical SSDE (gSSDE) and water-equivalent SSDE (wSSDE) values (P < 0.001), while the FLASH technique had lower values. No significant effective dose difference existed between prospective and FLASH techniques (P = 0.17), but significant differences were observed between FLASH vs. retrospective and prospective vs. retrospective (both P < 0.001). Gender did not significantly affect dose values. Correlation analysis showed poor correlations between gSSDE, wSSDE, related effective diameters, and factors like age, kV, and mAs.
Conclusion
This study highlights the importance of radiation dose consideration in selecting appropriate CCTA technique based on patient factors. The results showed that FLASH has the lowest doses, and incorporating SSDE improves dose accuracy. Our findings support the adoption of SSDE to optimize imaging protocols and enhance patient safety in cardiovascular imaging.
期刊介绍:
Radiation Physics and Chemistry is a multidisciplinary journal that provides a medium for publication of substantial and original papers, reviews, and short communications which focus on research and developments involving ionizing radiation in radiation physics, radiation chemistry and radiation processing.
The journal aims to publish papers with significance to an international audience, containing substantial novelty and scientific impact. The Editors reserve the rights to reject, with or without external review, papers that do not meet these criteria. This could include papers that are very similar to previous publications, only with changed target substrates, employed materials, analyzed sites and experimental methods, report results without presenting new insights and/or hypothesis testing, or do not focus on the radiation effects.