Exploring the multifaceted bioactivities of silver nanoparticles synthesized from red algae Hypnea pannosa: Antimicrobial, antibiofilm, and insecticidal potentials

IF 2.3 4区生物学 Q3 BIOTECHNOLOGY & APPLIED MICROBIOLOGY

Electronic Journal of Biotechnology Pub Date : 2025-03-01 DOI:10.1016/j.ejbt.2024.12.001

Mansour A.E. Bashar , Enas M.H. Attia , Alsayed E. Mekky , Tharwat A. Selim , Walaa M. Shaban , Mohamed A.M. El-Tabakh , Ammar.M. Mahmoud , Mostafa A. Abdel-Maksoud , Ali A. Ali , Mohamed A. El-Tayeb , Waleed B. Suleiman , Mohamed E. El Beeh , Sabiha Fatima , Bushra Hafeez Kiani , Nehal M. Khairy , Ebrahim Saied

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引用次数: 0

Abstract

Background

The emergence of microbial resistance to conventional antibiotics and the environmental impact of chemical pesticides necessitates the search for alternative and sustainable solutions. This study explores the utilization of the dried biomass of the red algae Hypnea pannosa to synthesize silver nanoparticles (AgNPs) using a green and eco-friendly method.

Results

The synthesized AgNPs displayed sizes ranging from 15 to 60 nm with polydispersed shapes and a face-centered cubic crystalline structure, confirmed through characterization techniques including transmission electron microscopy (TEM), dynamic light scattering (DLS), and X-ray diffraction (XRD). Stability assessments via zeta potential measurements and docking studies of oleic acid and 9,12-octadecadienoic acid against Gyrase B and GST proteins were also conducted. The nanoparticles demonstrated potent antibacterial and antibiofilm activities, particularly against Staphylococcus epidermidis. Both the algal extract and the AgNPs exhibited significant larvicidal and adulticidal effects against Culex pipiens, with the nanoparticles showing superior efficacy, indicated by lower LC50 and LC90 values. The highest larvicidal effectiveness achieved was 93.33% for algal extract at 600 mg/L and 100% for AgNPs at 100 mg/L.

Conclusions

This study provides a sustainable method for producing AgNPs with diverse applications in medical and mosquito control fields, highlighting their potential as effective and safe alternatives to conventional antibacterial and insecticidal agents.

How to cite: Bashar MA, Attia EM, Mekky AE, et al. Exploring the multifaceted bioactivities of silver nanoparticles synthesized from red algae Hypnea pannosa: Antimicrobial, antibiofilm, and insecticidal potentials. Electron J Biotechnol 2025;74. https://doi.org/10.1016/j.ejbt.2024.12.001.

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来源期刊

Electronic Journal of Biotechnology 工程技术-生物工程与应用微生物

CiteScore

5.60

自引率

0.00%

发文量

审稿时长

2 months

期刊介绍： Electronic Journal of Biotechnology is an international scientific electronic journal, which publishes papers from all areas related to Biotechnology. It covers from molecular biology and the chemistry of biological processes to aquatic and earth environmental aspects, computational applications, policy and ethical issues directly related to Biotechnology. The journal provides an effective way to publish research and review articles and short communications, video material, animation sequences and 3D are also accepted to support and enhance articles. The articles will be examined by a scientific committee and anonymous evaluators and published every two months in HTML and PDF formats (January 15th , March 15th, May 15th, July 15th, September 15th, November 15th). The following areas are covered in the Journal: • Animal Biotechnology • Biofilms • Bioinformatics • Biomedicine • Biopolicies of International Cooperation • Biosafety • Biotechnology Industry • Biotechnology of Human Disorders • Chemical Engineering • Environmental Biotechnology • Food Biotechnology • Marine Biotechnology • Microbial Biotechnology • Molecular Biology and Genetics •Nanobiotechnology • Omics • Plant Biotechnology • Process Biotechnology • Process Chemistry and Technology • Tissue Engineering