The GC MS Study of One Ayurvedic Formulation, Navayasa Churnam.

Abstract

Background: Navayasa Churnam is an Ayurvedic medicine traditionally used to treat anemia, heart diseases, skin disorders, piles, and jaundice.

Aim: The present study involves GC-MS analysis of Navayasa Churnam, an Ayurvedic medicine traditionally used to treat anemia, heart diseases, skin disorders, piles, and jaundice.

Methods: The Churnam was sourced from a reputable Ayurvedic vendor in Chennai, India, and prepared according to standard protocols. The medicine was then analyzed to identify its bioactive compounds.

Results: The GC-MS analysis revealed several key compounds, including Asarone, known for its sedative and antioxidant properties; 17-Octadecynoic acid methyl ester, with potential anti-inflammatory effects; n-Pentadecanol, recognized for its antimicrobial activity; and Chloroacetic acid pentadecyl ester, which may possess antiviral properties. Additional compounds identified include n-Butyl cinnamate, noted for its anti-inflammatory and antioxidant effects; Chloroacetic acid tetradecyl ester, which might offer antimicrobial benefits; and 2-ynyl o-anisate, known for its analgesic properties. Piperine, which enhances the bioavailability of other compounds and has anti-inflammatory effects, was also detected. Other notable compounds are Z-10-Methyl-11-tetradecen-1-ol propionate, Carnosic acid, and Ethyl iso-allocholate.

Conclusion: The identification of these compounds supports the traditional therapeutic uses of Navayasa Churnam and underscores the importance of integrating modern analytical techniques with traditional knowledge to validate and enhance herbal remedies.