Impact of the Physiological Parameters of the Oral Cavity on the Mechanical Properties of Zinc-stabilized and Zinc-free Adhesive Creams: A Comparative In Vitro Study.

Abstract

Purpose: The current trend in denture adhesives is shifting toward zinc-free formulations due to the significant health concerns associated with zinc. Studies have focused on the retention of these zinc-free denture adhesives; however, there is a dearth of literature regarding their damping performance. This study analyzes the impact of oral cavity physiological parameters: temperature, pH, and swelling ratio on the mechanical properties of zinc-stabilized and zinc-free denture adhesives and examines the role zinc plays in influencing the adhesive behavior. This study investigates how underlying mechanical properties of adhesive cream change for zinc-stabilized and zinc-free denture adhesives. The relative damping and its variation from exposure to physiological conditions in the oral cavity can significantly assist in the design of dentures to reduce the discomfort experienced by denture wearers.

Materials and methods: The relative damping of the zinc-stabilized and zinc-free denture adhesives was investigated with the loss modulus values, which were evaluated using rheological frequency sweep tests. The tests were performed by maintaining the denture adhesives at specified values of temperature, pH, and swelling ratio, and over a frequency range of 0.01 Hz to 10 Hz, which included the average frequencies of human chewing / bite forces reported in existing literature.

Results: Zinc-stabilized denture adhesive showed a larger fluctuation of loss modulus values compared to the zinc-free formulation with respect to pH, temperature, and swelling ratios. The zinc-free denture adhesive showed higher damping behavior at frequencies below 0.7 Hz, whereas the zinc-stabilized denture adhesive showed higher damping behavior above loading frequencies of 0.7-1 Hz. Both the adhesives showed varying behavior on either side of the bite force spectrum in terms of relative damping of the applied bite.

Conclusions: The damping or cushioning effect provided by denture adhesives can reduce pain experienced and assist dental practitioners in better supporting denture wearers.