Ji-Mei Wu, Ji-Hong Wu, Dan Liu, Xia Qin, Tu-Hong Yang
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引用次数: 0
Abstract
Introduction: This study examined lung function trajectory (FEV1 % predicted) in children with asthma and explored the influence of sex and asthma control on these trajectories.
Methods: A retrospective cohort study used a latent growth curve model (LGCM) to analyze the FEV1 trajectory in children with asthma.
Results: FEV1 followed a quadratic trajectory with significant individual variability. Males exhibited a significantly slower rate of FEV1 change compared to females (estimate = -1.029, p < .001) but a higher acceleration rate (estimate = 0.269, p < .001). Improved asthma control was associated with a significant enhancement in FEV1 over time (p < .01).
Discussion: FEV1 growth followed a curvilinear trajectory, marked by gradual deceleration. Males had slower initial growth but greater acceleration. Asthma control significantly influenced lung function improvement.
期刊介绍：
The Journal of Pediatric Health Care, the official journal of the National Association of Pediatric Nurse Practitioners, provides scholarly clinical information and research regarding primary, acute and specialty health care for children of newborn age through young adulthood within a family-centered context. The Journal disseminates multidisciplinary perspectives on evidence-based practice and emerging policy, advocacy and educational issues that are of importance to all healthcare professionals caring for children and their families.
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