Research progress on the mechanisms of acupuncture in improving ischemic stroke through autophagy.

Q3 Medicine

针刺研究 Pub Date : 2025-02-25 DOI:10.13702/j.1000-0607.20230791

Yu Wang, Yi-Ning Dai, Xiao-Jing Guo, Miao Hua, Li Zhang

引用次数: 0

Abstract

Stroke is a major disease with high incidence, disability rate, and mortality worldwide. In recent years, a large number of studies have comfirmed that acupuncture treatment for ischemic stroke is closely related to the regulation of autophagy mechanisms. This article summarizes the literature in recent years, discusses the effects of acupuncture on the degradation pathways mediated by autophagosomes, the expression of autophagy-related proteins, autophagy-related pathways, and the impact of mitophagy, and further explores the mechanisms of acupuncture in regulating autophagy to improve ischemic stroke, providing new ideas and schemes for clinical treatment.

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针刺通过自噬改善缺血性脑卒中机制的研究进展。

脑卒中是世界范围内发病率高、致残率高、死亡率高的主要疾病。近年来，大量研究证实，针刺治疗缺血性脑卒中与调节自噬机制密切相关。本文总结近年来的文献，探讨针刺对自噬体介导的降解途径、自噬相关蛋白的表达、自噬相关途径以及自噬对线粒体自噬的影响，并进一步探讨针刺调节自噬改善缺血性脑卒中的机制，为临床治疗提供新的思路和方案。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

针刺研究 Medicine-Medicine (all)

CiteScore

1.30

自引率

0.00%

发文量

期刊介绍： Acupuncture Research was founded in 1976. It is an acupuncture academic journal supervised by the State Administration of Traditional Chinese Medicine, co-sponsored by the Institute of Acupuncture of the China Academy of Chinese Medical Sciences and the Chinese Acupuncture Association. This journal is characterized by "basic experimental research as the main focus, taking into account clinical research and reporting". It is the only journal in my country that focuses on reporting the mechanism of action of acupuncture. The journal has been changed to a monthly journal since 2018, published on the 25th of each month, and printed in full color. The manuscript acceptance rate is about 10%, and provincial and above funded projects account for about 80% of the total published papers, reflecting the latest scientific research results in the acupuncture field and has a high academic level. Main columns: mechanism discussion, clinical research, acupuncture anesthesia, meridians and acupoints, theoretical discussion, ideas and methods, literature research, etc.