Updates in breathomics behavior in ischemic heart disease and heart failure, mass-spectrometry.

IF 1.9 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS

World Journal of Cardiology Pub Date : 2025-02-26 DOI:10.4330/wjc.v17.i2.102851

Basheer Abdualah Marzoog, Peter Chomakhidze, Daria Gognieva, Alena Yurievna Parunova, Snezhana Nikolaevna Demchuk, Artemiy Silantyev, Natalia Kuznetsova, Anastasia Kostikova, Dmitrii Podgalo, Evgeny Nagornov, Aida Gadzhiakhmedova, Philipp Kopylov

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引用次数: 0

Abstract

Background: Cardiovascular disease (CVD) and associated sequalae remain the leading cause of disability worldwide. Ischemic heart disease (IHD) and heart failure are the most common etiologies of morbidity and mortality worldwide. This is due to the poor diagnostic and management methods for heart failure and IHD. Early detection of related risk factors through modern strategies is underestimated and requires further research.

Aim: To interpret data from the published literature on volatile organic compounds (VOC), including all the methods used to analyze exhaled breath in patients with IHD and heart failure.

Methods: Searches for specific keywords were performed on Scopus and PubMed. A total of 20 studies were identified in breath analysis and IHD and heart failure. The study is registered in PROSPERO (Registration No. CRD42023470556).

Results: Considering the articles found, more research is required to gain a full understanding of the role of VOCs in IHD and heart failure. However, the existing literature demonstrates that cardiac metabolic changes can be expressed in exhaled air. The number of papers found is extremely low, making interpretation extremely difficult.

Conclusion: Exhaled breath analysis can be a novel biomarker for the diagnosis and prevention of heart failure and IHD. Exhaled breath analysis can be used as a mirror to reflect the metabolic changes related to IHD and heart failure.

查看原文本刊更多论文

缺血性心脏病和心力衰竭的呼吸组学行为的最新进展，质谱分析。

背景：心血管疾病（CVD）及其后遗症仍然是世界范围内致残的主要原因。缺血性心脏病（IHD）和心力衰竭是世界范围内发病率和死亡率最常见的病因。这是由于对心力衰竭和IHD的诊断和管理方法较差。通过现代战略早期发现相关风险因素的能力被低估了，需要进一步研究。目的：解读已发表的有关挥发性有机化合物（VOC）的文献数据，包括分析IHD和心力衰竭患者呼出气体的所有方法。方法：在Scopus和PubMed上检索特定关键词。共有20项研究在呼吸分析，IHD和心力衰竭中被确定。本研究注册号为普洛斯彼罗（PROSPERO）。CRD42023470556)。结果：考虑到已发现的文章，需要更多的研究来充分了解VOCs在IHD和心力衰竭中的作用。然而，现有文献表明，心脏代谢变化可以通过呼出的空气来表达。发现的论文数量非常少，这使得解释非常困难。结论：呼气分析可作为诊断和预防心力衰竭和IHD的一种新的生物标志物。呼气分析可以作为反映IHD和心力衰竭相关代谢变化的一面镜子。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

World Journal of Cardiology CARDIAC & CARDIOVASCULAR SYSTEMS-

CiteScore

3.30

自引率

5.30%

发文量