TAFRO Syndrome with Massive Bilateral Adrenal Hemorrhage.

IF 1.1 4区医学 Q3 MEDICINE, GENERAL & INTERNAL

Internal Medicine Pub Date : 2025-09-01 Epub Date: 2025-03-08 DOI:10.2169/internalmedicine.4823-24

Toshihiro Kobayashi, Hitomi Imachi, Kensaku Fukunaga, Takanobu Saheki, Takafumi Yoshimura, Kurumi Komori, Wenyi Jiang, Haotian Zhang, Rathana Ly, Ryou Ishikawa, Reiji Haba, Hiroaki Dobashi, Koji Murao

引用次数: 0

Abstract

We report the case of a 62-year-old man who presented with bilateral adrenal enlargement and systemic lymphadenopathy. Imaging and clinical findings led to the diagnosis of bilateral adrenal hemorrhage. Bone marrow aspiration and lymph node biopsy confirmed TAFRO syndrome, which met the established diagnostic criteria. Although adrenal hemorrhage in TAFRO syndrome is exceedingly rare, this case is unique, as it represents the first reported instance of massive bilateral adrenal hemorrhage with confirmed progression. This case underscores the need for awareness regarding this potential complication of TAFRO syndrome.

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TAFRO综合征合并双侧肾上腺大出血1例。

我们报告的情况下，62岁的男子谁提出了双侧肾上腺肿大和全身性淋巴结病。影像学和临床表现导致双侧肾上腺出血的诊断。骨髓穿刺及淋巴结活检证实TAFRO综合征，符合既定诊断标准。虽然TAFRO综合征中肾上腺出血极为罕见，但该病例是独一无二的，因为它是第一例报道的双侧大量肾上腺出血并确诊进展的病例。本病例强调需要认识到TAFRO综合征的这种潜在并发症。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Internal Medicine 医学-医学：内科

CiteScore

1.90

自引率

8.30%

发文量

审稿时长

2.2 months

期刊介绍： Internal Medicine is an open-access online only journal published monthly by the Japanese Society of Internal Medicine. Articles must be prepared in accordance with "The Uniform Requirements for Manuscripts Submitted to Biomedical Journals (see Annals of Internal Medicine 108: 258-265, 1988), must be contributed solely to the Internal Medicine, and become the property of the Japanese Society of Internal Medicine. Statements contained therein are the responsibility of the author(s). The Society reserves copyright and renewal on all published material and such material may not be reproduced in any form without the written permission of the Society.