Efficacy and Safety Evaluation of 595 nm Pulsed Dye Laser Treatment in 120 Cases of Asian Infants With Port Wine Stain.

IF 1.9 4区医学 Q3 DERMATOLOGY

Clinical, Cosmetic and Investigational Dermatology Pub Date : 2025-03-03 eCollection Date: 2025-01-01 DOI:10.2147/CCID.S489305

Yiqun Guo, Hua Jiang, Yizhou Jiang, Xiaoyun Tan, Haibo Li, Jiejun Xia, Zhen-Yin Liu

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引用次数: 0

Abstract

Introduction: This study aimed to evaluate the efficacy and safety of a 595 nm pulsed dye laser (PDL) for the treatment of port wine stain (PWS) in 120 Asian infant patients.

Methods: A retrospective analysis was carried out to assess the efficacy and safety of 595 nm PDL in 120 Asian infant patients with PWS.

Results: This study identified excellent (21.67%), good (23.33%), fair (30.83%), and poor (15.83%) clearance. Multiple treatments significantly improved efficacy, with 61.56% of patients achieving good or excellent responses after more than six sessions. Younger patients showed better treatment outcomes than older patients did. The lesion location influenced the response, with leg lesions exhibiting the poorest response. The pink lesions were the most susceptible, whereas the purple lesions displayed the least response. Smaller lesions (<10 cm²) showed a size-dependent excellent rate (41.0%) and lower poor rate (5.1%).

Conclusion: The 595 nm PDL treatment displayed a favorable safety profile, with only mild, well-tolerated adverse effects. Rare adverse effects were resolved within 3-6 months. No severe adverse events were reported. The 595 nm PDL is safe and effective for Asian infant patients with PWS. The side effects were mild and well-tolerated by the patients.

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来源期刊

Clinical, Cosmetic and Investigational Dermatology Medicine-Dermatology

CiteScore

2.80

自引率

4.30%

发文量

353

审稿时长

16 weeks

期刊介绍： Clinical, Cosmetic and Investigational Dermatology is an international, peer-reviewed, open access journal that focuses on the latest clinical and experimental research in all aspects of skin disease and cosmetic interventions. Normal and pathological processes in skin development and aging, their modification and treatment, as well as basic research into histology of dermal and dermal structures that provide clinical insights and potential treatment options are key topics for the journal. Patient satisfaction, preference, quality of life, compliance, persistence and their role in developing new management options to optimize outcomes for target conditions constitute major areas of interest. The journal is characterized by the rapid reporting of clinical studies, reviews and original research in skin research and skin care. All areas of dermatology will be covered; contributions will be welcomed from all clinicians and basic science researchers globally.