Silent escalation: The journey of Shigella from gut to blood

IF 1.4 4区医学 Q4 IMMUNOLOGY

Indian Journal of Medical Microbiology Pub Date : 2025-03-01 DOI:10.1016/j.ijmmb.2025.100815

Ekadashi Rajni , Snigdha Purohit , Rachna Priyadarshini , Gunjan Agarwal

引用次数: 0

Abstract

Shigella are Gram-negative non motile facultative anaerobic bacteria belonging to family Enterobacterales. They are a leading cause of diarrhoea and dysentery and constitute a significant public health problem in both the developing and developed nations. In Asia alone, 125 million infections and 14,000 deaths are estimated to be due to shigellosis annually. Bacteremia caused by Shigella spp is rare. We hereby present a case of bloodstream infection caused by fluoroquinolone resistant, extended spectrum beta lactamase producing Shigella flexneri strain in a five-year-old malnourished child that was successfully managed using meropenem and supportive treatment.

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无声升级：志贺氏菌从肠道到血液的旅程

志贺氏菌是革兰氏阴性非活动兼性厌氧细菌，属于肠杆菌科。它们是腹泻和痢疾的主要原因，在发展中国家和发达国家都构成一个重大的公共卫生问题。仅在亚洲，估计每年就有1.25亿人感染志贺氏菌病，14000人死亡。志贺氏菌引起的菌血症是罕见的。我们在此报告一例由氟喹诺酮耐药、广谱β内酰胺酶产生的福氏志贺氏菌引起的血液感染，患者为一名五岁营养不良儿童，使用美罗培南和支持性治疗成功治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Indian Journal of Medical Microbiology IMMUNOLOGY-

CiteScore

2.20

自引率

0.00%

发文量

154

审稿时长

73 days

期刊介绍： Manuscripts of high standard in the form of original research, multicentric studies, meta analysis, are accepted. Current reports can be submitted as brief communications. Case reports must include review of current literature, clinical details, outcome and follow up. Letters to the editor must be a comment on or pertain to a manuscript already published in the IJMM or in relation to preliminary communication of a larger study. Review articles, Special Articles or Guest Editorials are accepted on invitation.