Color vision-associated environmental and biological factors in the development of myopia

IF 3 2区医学 Q1 OPHTHALMOLOGY

Experimental eye research Pub Date : 2025-03-07 DOI:10.1016/j.exer.2025.110324

Dongjie Song , Qianjie Yang , Jiayun Ge , Kuangqi Chen , Jianping Tong , Ye Shen

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Abstract

As a global public health problem, myopia has attracted more and more attention for its high prevalence and severe visual impairment. Although extensive research on the risk factors for myopia has been conducted, the underlying pathogenesis is still unclear. Color vision, mediated by retinal cone cells, is a fundamental and important component of human visual functions. Indeed, numerous studies implicate color vision-associated environmental and biological factors in myopia pathogenesis, indicating that related interventions may delay myopia progression. Studies have shown that color vision can induce different accommodation responses under near work conditions and exert opposite effects in different light environments to influence myopia advancement. Besides, color vision-related genes and metabolites are proven to be correlated with myopia. This review aims to make detailed elaborations on the role of color vision in myopia and its potential interaction mechanism, hoping to provide new ideas for myopia prevention.

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色觉相关的环境和生物因素在近视发展中的作用

近视作为一个全球性的公共卫生问题，因其高发病率和严重的视力损害而受到越来越多的关注。虽然对近视的危险因素进行了广泛的研究，但其潜在的发病机制尚不清楚。视锥细胞介导的色觉是人类视觉功能的重要组成部分。事实上，大量的研究表明，色觉相关的环境和生物因素在近视的发病机制中起作用，表明相关的干预措施可能延缓近视的发展。研究表明，色觉在近工作条件下诱导不同的调节反应，而在不同的光环境下发挥相反的作用，影响近视的进展。此外，色觉相关基因和代谢物也被证实与近视相关。本文旨在详细阐述色觉在近视中的作用及其可能的相互作用机制，以期为近视预防提供新的思路。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Experimental eye research 医学-眼科学

CiteScore

6.80

自引率

5.90%

发文量

323

审稿时长

66 days

期刊介绍： The primary goal of Experimental Eye Research is to publish original research papers on all aspects of experimental biology of the eye and ocular tissues that seek to define the mechanisms of normal function and/or disease. Studies of ocular tissues that encompass the disciplines of cell biology, developmental biology, genetics, molecular biology, physiology, biochemistry, biophysics, immunology or microbiology are most welcomed. Manuscripts that are purely clinical or in a surgical area of ophthalmology are not appropriate for submission to Experimental Eye Research and if received will be returned without review.