Decoding the transcriptional regulatory mechanisms of basic helix–loop–helix transcription factors for fine-tuning target genes in rice

IF 6.1 2区生物学 Q1 PLANT SCIENCES

Plant Physiology and Biochemistry Pub Date : 2025-03-03 DOI:10.1016/j.plaphy.2025.109696

Sunok Moon , Xu Jiang , Heebak Choi, Sun-Hwa Ha, Ki-Hong Jung

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引用次数: 0

Abstract

Background

In the intricate landscape of gene regulation, basic helix-loop-helix (bHLH) transcription factors (TFs) play a pivotal role in controlling gene expression across various biological processes in plants. The bHLH domain, about 60 amino acids long, consists of a DNA-binding basic region and a dimerization helix-loop-helix region. In rice, 188 bHLH proteins are encoded and more than 90 functionally characterized. To finely regulate the expression of various target genes, bHLH TFs engage multiple transcriptional regulatory mechanisms.

Aim of review

The aim of this review is to provide a comprehensive understanding of the diverse transcriptional regulatory mechanisms of bHLH TFs in rice.

Key scientific concepts of review

bHLH TFs engage the diverse transcriptional regulatory mechanisms, including spatiotemporal expression, the formation of inhibitory complexes, and the integration multiple signaling pathways. Additionally, the ability to switch interaction partners provides flexibility in target site recognition, allowing bHLH proteins regulate a wide range of biological processes, from basic cellular functions to complex developmental pathways. Understanding of multiple transcriptional regulatory mechanisms of bHLH TFs can provide key insights for improving crop traits, such as stress resistance and growth efficiency, which are crucial for enhancing agricultural productivity in the future.

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来源期刊

Plant Physiology and Biochemistry 生物-植物科学

CiteScore

11.10

自引率

3.10%

发文量

410

审稿时长

33 days

期刊介绍： Plant Physiology and Biochemistry publishes original theoretical, experimental and technical contributions in the various fields of plant physiology (biochemistry, physiology, structure, genetics, plant-microbe interactions, etc.) at diverse levels of integration (molecular, subcellular, cellular, organ, whole plant, environmental). Opinions expressed in the journal are the sole responsibility of the authors and publication does not imply the editors'' agreement. Manuscripts describing molecular-genetic and/or gene expression data that are not integrated with biochemical analysis and/or actual measurements of plant physiological processes are not suitable for PPB. Also "Omics" studies (transcriptomics, proteomics, metabolomics, etc.) reporting descriptive analysis without an element of functional validation assays, will not be considered. Similarly, applied agronomic or phytochemical studies that generate no new, fundamental insights in plant physiological and/or biochemical processes are not suitable for publication in PPB. Plant Physiology and Biochemistry publishes several types of articles: Reviews, Papers and Short Papers. Articles for Reviews are either invited by the editor or proposed by the authors for the editor''s prior agreement. Reviews should not exceed 40 typewritten pages and Short Papers no more than approximately 8 typewritten pages. The fundamental character of Plant Physiology and Biochemistry remains that of a journal for original results.