3D non-contrast whole‑heart coronary MR angiography at 3 T with compressed sensing in elderly patients: Optimization of the acceleration factor

IF 1.8 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

European Journal of Radiology Open Pub Date : 2025-03-08 DOI:10.1016/j.ejro.2025.100641

Yue Jiang , Qiuju Hu , Yane Zhao , Dongsheng Jin , Guangming Lu , Tong Chen , Yong Yuan , Wenjing Liu

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引用次数: 0

Abstract

Background

Coronary magnetic resonance angiography (CMRA) is increasingly used in clinical practice, but lengthy scan times can be challenging for elderly patients. This study evaluates the impact of compressed sensing (CS) technology on image quality and diagnostic performance of 3 T CMRA in elderly patients, aiming to identify the optimal acceleration factor.

Methods

We prospectively enrolled elderly individuals who underwent coronary computed tomography angiography (CCTA) from June to November 2023 for non-contrast whole-heart CMRA with CS acceleration factors of 4, 6, or 8. Elderly volunteers rated their experiences with the optimal acceleration factor. Image quality and diagnostic performance were analyzed using a general linear model and the area under the receiver operating characteristic curves (AUC), with CCTA as the reference standard.

Results

Sixty-seven individuals (34 men, mean age 74.3 ± 7.2 years) were enrolled. Scan times significantly decreased from 578.6 ± 131.4 s to 366.1 ± 91.2 s and 261.1 ± 76.5 s for acceleration factors 4, 6, and 8, respectively. Subjective image quality scores, signal-to-noise ratio, and contrast-to-noise ratio were significantly better with CS4 and CS6 than with CS8. Diagnostic performance declined with increasing acceleration, with sensitivities of 92.2 %, 88.0 %, and 72.5 %, and specificities of 94.1 %, 92.6 %, and 85.3 % for CS4, CS6, and CS8, respectively. CS6 was determined to be the optimal acceleration factor. Volunteers reported that CS6 was more acceptable than CS4.

Conclusions

CMRA with CS6 provides rapid scanning while maintaining adequate diagnostic performance, making it a reliable alternative to CCTA for diagnosing coronary artery disease in elderly patients.

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三维无对比全心冠状动脉磁共振血管造影在3 T与压缩传感在老年患者：优化加速因子

冠状动脉磁共振血管造影（CMRA）越来越多地应用于临床实践，但长时间的扫描时间对老年患者来说是一个挑战。本研究评估压缩感知（CS）技术对老年患者3 T CMRA图像质量和诊断性能的影响，旨在确定最佳加速因子。方法：我们前瞻性地招募了于2023年6月至11月接受冠状动脉计算机断层血管造影（CCTA）的老年人，进行非对比全心CMRA， CS加速因子为4、6或8。老年志愿者用最佳加速系数来评价他们的经历。以CCTA为参考标准，采用一般线性模型和接收机工作特征曲线下面积（AUC）对图像质量和诊断性能进行分析。结果共纳入67例，男性34例，平均年龄74.3 ± 7.2岁。扫描时间大大减少从578.6 ±131.4  年代 366.1±91.2   年代和261.1±76.5  年代加速因素4、6和8位。CS4、CS6的主观图像质量评分、信噪比、对比噪比均明显优于CS8。诊断性能随着加速的增加而下降，对CS4、CS6和CS8的敏感性分别为92.2 %、88.0 %和72.5 %，特异性分别为94.1 %、92.6 %和85.3 %。确定CS6为最优加速因子。志愿者报告CS6比CS4更容易接受。结论scmra与CS6在快速扫描的同时保持了足够的诊断性能，是替代CCTA诊断老年患者冠状动脉疾病的可靠方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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