Leul Adane , Michael A. Negussie , Dagmawit Fikire
{"title":"Imaging features of juvenile dermatomyositis complicated by pyomyositis in a 12-year-old boy: A case report","authors":"Leul Adane , Michael A. Negussie , Dagmawit Fikire","doi":"10.1016/j.radcr.2025.02.010","DOIUrl":null,"url":null,"abstract":"<div><div>Juvenile dermatomyositis (JDM) is a rare autoimmune disorder characterized by chronic inflammation of the skin and skeletal muscles, often complicated by systemic manifestations and secondary infections. This case report describes a 12-year-old boy with a history of JDM who developed pyomyositis, a rare bacterial infection of skeletal muscles, following immunosuppressive therapy with methotrexate and low-dose steroids. The patient presented with fever, swelling, and tenderness in the left leg, with imaging confirming abscess formation. A multidisciplinary approach was employed for management, including surgical drainage and targeted antibiotic therapy. This case highlights the diagnostic and therapeutic challenges of managing pyomyositis in JDM, emphasizing the increased infection risk associated with immunosuppressive treatments and the importance of early intervention to prevent complications.</div></div>","PeriodicalId":53472,"journal":{"name":"Radiology Case Reports","volume":"20 5","pages":"Pages 2540-2543"},"PeriodicalIF":0.0000,"publicationDate":"2025-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Radiology Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1930043325001086","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Juvenile dermatomyositis (JDM) is a rare autoimmune disorder characterized by chronic inflammation of the skin and skeletal muscles, often complicated by systemic manifestations and secondary infections. This case report describes a 12-year-old boy with a history of JDM who developed pyomyositis, a rare bacterial infection of skeletal muscles, following immunosuppressive therapy with methotrexate and low-dose steroids. The patient presented with fever, swelling, and tenderness in the left leg, with imaging confirming abscess formation. A multidisciplinary approach was employed for management, including surgical drainage and targeted antibiotic therapy. This case highlights the diagnostic and therapeutic challenges of managing pyomyositis in JDM, emphasizing the increased infection risk associated with immunosuppressive treatments and the importance of early intervention to prevent complications.
期刊介绍:
The content of this journal is exclusively case reports that feature diagnostic imaging. Categories in which case reports can be placed include the musculoskeletal system, spine, central nervous system, head and neck, cardiovascular, chest, gastrointestinal, genitourinary, multisystem, pediatric, emergency, women''s imaging, oncologic, normal variants, medical devices, foreign bodies, interventional radiology, nuclear medicine, molecular imaging, ultrasonography, imaging artifacts, forensic, anthropological, and medical-legal. Articles must be well-documented and include a review of the appropriate literature.