Tinnitus, masked speech perception, and auditory event-related potentials in clinically normal-hearing adults

IF 2.5 2区医学 Q1 AUDIOLOGY & SPEECH-LANGUAGE PATHOLOGY

Hearing Research Pub Date : 2025-03-07 DOI:10.1016/j.heares.2025.109239

Ning Gao , Sheng-Yu Tao , Qian-Jie Fu , John Galvin , Sean Lang , Ya-Feng Yu , Ji-Sheng Liu , Duo-Duo Tao

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引用次数: 0

Abstract

Tinnitus can increase stress and anxiety and reduce quality of life. Compared to listeners with normal hearing and no tinnitus, listeners with tinnitus (with or without hearing loss) often have greater difficulty segregating competing speech. Previous studies have investigated neural correlates of tinnitus using the P3 component of event-related potentials (ERPs). Speech reception thresholds (SRTs) and ERPs were measured in 29 listeners with tinnitus and 25 listeners without tinnitus; all were clinically normal hearing, with pure-tone average (PTA) thresholds <25 dB HL across 500, 1000, 2000, and 4000 Hz. SRTs for a male target talker were measured in speech-shaped noise (SSN; energetic masking) or with a single female speech masker (informational masking). Auditory ERPs were measured for a 1 kHz vs. 2 kHz contrast. SRTs in competing speech were significantly lower for the non-tinnitus than for the tinnitus group (p = 0.042); there was no significant group difference for SRTs in SSN. Latency was significantly longer for the tinnitus than for the non-tinnitus group for N1 (p = 0.034) and P3 (p < 0.001), but not for P2. There were no significant group differences in terms of P2-N1 or P3 amplitude. Multilinear regression analysis showed that age at testing (p = 0.005), N1 latency (p = 0.031), P3 latency (p = 0.020), and P3 amplitude (p = 0.031) were significant predictors of SRTs in competing speech. The present results suggest that among adults with clinically normal PTAs, susceptibility to informational masking may be greater for listeners with than without tinnitus.

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临床听力正常成人的耳鸣、隐瞒性言语知觉和听觉事件相关电位

耳鸣会增加压力和焦虑，降低生活质量。与听力正常且没有耳鸣的听众相比，耳鸣听众（有或没有听力损失）通常更难以区分竞争性语言。以往的研究利用事件相关电位（ERPs）的P3分量来研究耳鸣的神经相关性。测量29例耳鸣患者和25例非耳鸣患者的语音接收阈值（srt）和erp；所有患者临床听力正常，500、1000、2000和4000 Hz的纯音平均（PTA）阈值为25 dB HL。用语音形状噪声（SSN）测量男性目标说话者的srt；能量掩蔽)或与一个女性语音掩蔽者（信息掩蔽）。以1 kHz和2 kHz对比测量听觉erp。非耳鸣组竞争言语的srt显著低于耳鸣组（p = 0.042）；srt的SSN组间差异无统计学意义。耳鸣组N1潜伏期明显长于非耳鸣组（p = 0.034）， P3潜伏期明显长于非耳鸣组(p <；0.001)，但P2并非如此。P2-N1和P3振幅组间差异无统计学意义。多元线性回归分析显示，测试年龄（p = 0.005）、N1潜伏期（p = 0.031）、P3潜伏期（p = 0.020）和P3振幅（p = 0.031）是竞争言语中srt的显著预测因子。目前的结果表明，在临床上耳鸣正常的成年人中，有耳鸣的听者对信息掩蔽的易感性可能比没有耳鸣的听者更大。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Hearing Research 医学-耳鼻喉科学

CiteScore

5.30

自引率

14.30%

发文量

163

审稿时长

75 days

期刊介绍： The aim of the journal is to provide a forum for papers concerned with basic peripheral and central auditory mechanisms. Emphasis is on experimental and clinical studies, but theoretical and methodological papers will also be considered. The journal publishes original research papers, review and mini- review articles, rapid communications, method/protocol and perspective articles. Papers submitted should deal with auditory anatomy, physiology, psychophysics, imaging, modeling and behavioural studies in animals and humans, as well as hearing aids and cochlear implants. Papers dealing with the vestibular system are also considered for publication. Papers on comparative aspects of hearing and on effects of drugs and environmental contaminants on hearing function will also be considered. Clinical papers will be accepted when they contribute to the understanding of normal and pathological hearing functions.