{"title":"Effectiveness of acupoint injection combined with specific electromagnetic spectrum irradiation and acupuncture on peripheral facial paralysis.","authors":"Meihua Sun, Mingli Ge, Qinglin Shen","doi":"10.1080/01616412.2025.2476515","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To investigate the clinical effectiveness of acupoint injection in the treatment of acute phase of peripheral facial paralysis (PFP).</p><p><strong>Methods: </strong>A total of 85 patients with PFP were randomly divided into the control group, which was treated by prednisone acetate; the thermal design power (TDP) group, which was treated with acupuncture plus specific electromagnetic spectrum irradiation; and the acupoint injection group, which was treated with acupuncture plus specific electromagnetic spectrum irradiation combined with vitamin B1 (Vit B1) and vitamin B12 (Vit B12) acupoint injection. The treatment effectiveness was evaluated by Portmann score of facial paralysis, House-Brackmann (H-B) facial nerve function grading, serum levels of IL-6, IL-1β, and TNF-α, the cure time, and total effective rate.</p><p><strong>Results: </strong>The scores of Portmann and H-B in the TDP group were significantly higher than the control group, and the acupoint injection group was higher than the TDP group after each course of treatment (<i>p</i> < 0.05). The time to produce a significant effectiveness was shortened in the order of the acupoint injection group > the TDP group > the control group (<i>p</i> < 0.05). The cure rate was higher in the acupoint injection group (100%) than the TDP group (72.41%) and control group (67.86%) (<i>p</i> < 0.05). The serum levels of IL-6, IL-1β and TNF-α were obviously lower in the TDP group than the control group and in the acupoint injection group were lower than the TDP group (<i>p</i> < 0.05).</p><p><strong>Conclusion: </strong>Acupoint injection can significantly improve the curative effect, shorten the cure time, reduce the level of serum inflammatory factors, and promote the recovery of facial nerve function in the acute stage of PFP.</p>","PeriodicalId":19131,"journal":{"name":"Neurological Research","volume":" ","pages":"1-8"},"PeriodicalIF":1.7000,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neurological Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/01616412.2025.2476515","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Objective: To investigate the clinical effectiveness of acupoint injection in the treatment of acute phase of peripheral facial paralysis (PFP).
Methods: A total of 85 patients with PFP were randomly divided into the control group, which was treated by prednisone acetate; the thermal design power (TDP) group, which was treated with acupuncture plus specific electromagnetic spectrum irradiation; and the acupoint injection group, which was treated with acupuncture plus specific electromagnetic spectrum irradiation combined with vitamin B1 (Vit B1) and vitamin B12 (Vit B12) acupoint injection. The treatment effectiveness was evaluated by Portmann score of facial paralysis, House-Brackmann (H-B) facial nerve function grading, serum levels of IL-6, IL-1β, and TNF-α, the cure time, and total effective rate.
Results: The scores of Portmann and H-B in the TDP group were significantly higher than the control group, and the acupoint injection group was higher than the TDP group after each course of treatment (p < 0.05). The time to produce a significant effectiveness was shortened in the order of the acupoint injection group > the TDP group > the control group (p < 0.05). The cure rate was higher in the acupoint injection group (100%) than the TDP group (72.41%) and control group (67.86%) (p < 0.05). The serum levels of IL-6, IL-1β and TNF-α were obviously lower in the TDP group than the control group and in the acupoint injection group were lower than the TDP group (p < 0.05).
Conclusion: Acupoint injection can significantly improve the curative effect, shorten the cure time, reduce the level of serum inflammatory factors, and promote the recovery of facial nerve function in the acute stage of PFP.
期刊介绍:
Neurological Research is an international, peer-reviewed journal for reporting both basic and clinical research in the fields of neurosurgery, neurology, neuroengineering and neurosciences. It provides a medium for those who recognize the wider implications of their work and who wish to be informed of the relevant experience of others in related and more distant fields.
The scope of the journal includes:
•Stem cell applications
•Molecular neuroscience
•Neuropharmacology
•Neuroradiology
•Neurochemistry
•Biomathematical models
•Endovascular neurosurgery
•Innovation in neurosurgery.