Thalidomide as Treatment of Lip's Pyogenic Granuloma.

IF 0.7 Q3 MEDICINE, GENERAL & INTERNAL
International Medical Case Reports Journal Pub Date : 2025-03-01 eCollection Date: 2025-01-01 DOI:10.2147/IMCRJ.S511053
Liyan Lai, Jiayao Nie, Dejian Duan, Dan Huang
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引用次数: 0

Abstract

Pyogenic granuloma (PG) is a benign vascular tumor that can be challenging to treat, particularly in aesthetically sensitive areas. We report a case of a 32-year-old man with a PG on the upper lip that did not respond to conventional treatments, including glucocorticoid injections and long-pulse 1064 nm laser therapy. Due to aesthetic concerns and the lack of response to these treatments, the patient was administered oral thalidomide at a nightly dose of 75 mg for 5 months, which resulted in complete regression without recurrence over a 3-year follow-up. This case suggests thalidomide's potential as an effective alternative treatment for PG in sensitive areas.

沙利度胺治疗唇部化脓性肉芽肿。
化脓性肉芽肿(PG)是一种良性血管肿瘤,具有挑战性的治疗,特别是在审美敏感的区域。我们报告一例32岁男性上唇PG,常规治疗无效,包括糖皮质激素注射和长脉冲1064nm激光治疗。由于美观方面的考虑和对这些治疗缺乏反应,患者服用沙利度胺,每晚口服75毫克,持续5个月,在3年的随访中完全消退,无复发。本病例提示沙利度胺作为敏感部位PG的有效替代治疗方法的潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
International Medical Case Reports Journal
International Medical Case Reports Journal MEDICINE, GENERAL & INTERNAL-
CiteScore
1.40
自引率
0.00%
发文量
135
审稿时长
16 weeks
期刊介绍: International Medical Case Reports Journal is an international, peer-reviewed, open access, online journal publishing original case reports from all medical specialties. Submissions should not normally exceed 3,000 words or 4 published pages including figures, diagrams and references. As of 1st April 2019, the International Medical Case Reports Journal will no longer consider meta-analyses for publication.
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