Coronary Inflammation and Cardiovascular Events in Patients Without Obstructive Coronary Artery Disease.

IF 3.1 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Current Cardiology Reports Pub Date : 2025-03-07 DOI:10.1007/s11886-025-02221-y

Jia Ling Diau, Richard A Lange

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引用次数: 0

Abstract

Purpose of review: This review evaluates the role of vascular inflammation in patients who develop myocardial infarction with non-obstructive coronary arteries (MINOCA). It also introduces pericoronary adipose tissue (PCAT) and epicardial adipose tissue (EAT) as possible biomarkers for risk prediction in patients with non-obstructive coronary artery disease (CAD).

Recent findings: PCAT and EAT contribute to the development and progression of coronary artery inflammation and plaque vulnerability. Coronary computed tomography angiography (CCTA) can detect localized areas of inflammation through changes in the attenuation values of PCAT and EAT. Attenuation values can be further integrated with traditional risk factors using artificial intelligence to generate risk scores that significantly enhance prognostic accuracy in patients with and without obstructive coronary artery disease. Assessing PCAT and EAT inflammation via CCTA and AI-driven risk algorithms enable precise risk prediction of MINOCA and major adverse coronary events (MACE) in patients with non-obstructive CAD.

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无阻塞性冠状动脉疾病患者的冠状动脉炎症和心血管事件

综述目的：本综述评价血管炎症在伴有非阻塞性冠状动脉（MINOCA）的心肌梗死患者中的作用。它还引入了冠状动脉周围脂肪组织（PCAT）和心外膜脂肪组织（EAT）作为非阻塞性冠状动脉疾病（CAD）患者风险预测的可能生物标志物。最近的研究发现：PCAT和EAT有助于冠状动脉炎症和斑块易损性的发生和进展。冠状动脉ct血管造影（CCTA）可以通过PCAT和EAT衰减值的变化来检测局部炎症区域。衰减值可以进一步与传统的危险因素结合使用人工智能生成风险评分，显著提高有或无阻塞性冠状动脉疾病患者的预后准确性。通过CCTA和ai驱动的风险算法评估PCAT和EAT炎症，可以精确预测非阻塞性CAD患者的MINOCA和主要不良冠状动脉事件（MACE）的风险。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Cardiology Reports CARDIAC & CARDIOVASCULAR SYSTEMS-

CiteScore

6.20

自引率

2.70%

发文量

209

期刊介绍： The aim of this journal is to provide timely perspectives from experts on current advances in cardiovascular medicine. We also seek to provide reviews that highlight the most important recently published papers selected from the wealth of available cardiovascular literature. We accomplish this aim by appointing key authorities in major subject areas across the discipline. Section editors select topics to be reviewed by leading experts who emphasize recent developments and highlight important papers published over the past year. An Editorial Board of internationally diverse members suggests topics of special interest to their country/region and ensures that topics are current and include emerging research. We also provide commentaries from well-known figures in the field.