Daily Heart Rate Variability in Dogs With Atrial Fibrillation

IF 2.1 2区 农林科学 Q1 VETERINARY SCIENCES
Joao Escalda, Brigite Pedro, Jose Novo Matos, Antonia Mavropoulou, Christopher Linney, Joao Neves, Joanna Dukes-McEwan, Anna R. Gelzer
{"title":"Daily Heart Rate Variability in Dogs With Atrial Fibrillation","authors":"Joao Escalda,&nbsp;Brigite Pedro,&nbsp;Jose Novo Matos,&nbsp;Antonia Mavropoulou,&nbsp;Christopher Linney,&nbsp;Joao Neves,&nbsp;Joanna Dukes-McEwan,&nbsp;Anna R. Gelzer","doi":"10.1111/jvim.70051","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Background</h3>\n \n <p>Daily variability of heart rate in 24-h Holter recordings in dogs with atrial fibrillation (AF) receiving antiarrhythmic drugs (AAD) is unknown and could influence medical decisions.</p>\n </section>\n \n <section>\n \n <h3> Hypothesis/Objectives</h3>\n \n <p>Dogs with AF, Holter-derived mean heart rate (meanHRHolter) over 24 h is not significantly different from a subsequent, consecutive 24-h period.</p>\n </section>\n \n <section>\n \n <h3> Animals</h3>\n \n <p>Twenty-five dogs with AF.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>Prospective, descriptive, multicenter study. MeanHRHolter rate and ventricular arrhythmias (VAs) were prospectively analyzed after starting AAD. Clinically relevant difference (defined as ≥ 10 bpm in the meanHRHolter), success of rate control (defined as meanHRHolter ≤ 125 bpm). A Bland–Altman analysis and intra-class correlation coefficient (ICC) were calculated to compare two consecutive 24-h Holter recordings. VAs percentage difference [(maximum daily value-minimum daily value)/maximum daily value × 100] and grading variability between recordings were also investigated.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>Small BIAS with ICC 0.98 (95% confidence interval [CI] 0.95–0.99) on meanHRHolter with no statistical difference between two consecutive 24-h Holter recordings (95% CI [−2.84–2.92], degree of freedom 24, <i>p</i> = 0.98). Only 2/25 dogs (8%; 95% CI [2%–25%]) had clinically significant variation, while 1/25 (4%; 95% CI [0%–20%]) dogs showed different classifications in the success of rate control between the consecutive recordings. The VAs percentage difference was 52%, with 7/25 (28%; 95% CI [14%–47%]) dogs showing a VAs grading difference of ≥ 2.</p>\n </section>\n \n <section>\n \n <h3> Conclusion and Clinical Importance</h3>\n \n <p>The daily heart rate variability in dogs with AF receiving AAD is low, suggesting that a single 24-h Holter recording is adequate to assess rate control. Daily variability might be an important consideration when assessing VAs in dogs with concomitant AF.</p>\n </section>\n </div>","PeriodicalId":49958,"journal":{"name":"Journal of Veterinary Internal Medicine","volume":"39 2","pages":""},"PeriodicalIF":2.1000,"publicationDate":"2025-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jvim.70051","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Veterinary Internal Medicine","FirstCategoryId":"97","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/jvim.70051","RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
引用次数: 0

Abstract

Background

Daily variability of heart rate in 24-h Holter recordings in dogs with atrial fibrillation (AF) receiving antiarrhythmic drugs (AAD) is unknown and could influence medical decisions.

Hypothesis/Objectives

Dogs with AF, Holter-derived mean heart rate (meanHRHolter) over 24 h is not significantly different from a subsequent, consecutive 24-h period.

Animals

Twenty-five dogs with AF.

Methods

Prospective, descriptive, multicenter study. MeanHRHolter rate and ventricular arrhythmias (VAs) were prospectively analyzed after starting AAD. Clinically relevant difference (defined as ≥ 10 bpm in the meanHRHolter), success of rate control (defined as meanHRHolter ≤ 125 bpm). A Bland–Altman analysis and intra-class correlation coefficient (ICC) were calculated to compare two consecutive 24-h Holter recordings. VAs percentage difference [(maximum daily value-minimum daily value)/maximum daily value × 100] and grading variability between recordings were also investigated.

Results

Small BIAS with ICC 0.98 (95% confidence interval [CI] 0.95–0.99) on meanHRHolter with no statistical difference between two consecutive 24-h Holter recordings (95% CI [−2.84–2.92], degree of freedom 24, p = 0.98). Only 2/25 dogs (8%; 95% CI [2%–25%]) had clinically significant variation, while 1/25 (4%; 95% CI [0%–20%]) dogs showed different classifications in the success of rate control between the consecutive recordings. The VAs percentage difference was 52%, with 7/25 (28%; 95% CI [14%–47%]) dogs showing a VAs grading difference of ≥ 2.

Conclusion and Clinical Importance

The daily heart rate variability in dogs with AF receiving AAD is low, suggesting that a single 24-h Holter recording is adequate to assess rate control. Daily variability might be an important consideration when assessing VAs in dogs with concomitant AF.

Abstract Image

房颤犬的日心率变异性
背景:接受抗心律失常药物(AAD)治疗的房颤(AF)犬24小时动态心电图记录的每日心率变异性尚不清楚,可能影响医疗决策。假设/目的:患有房颤的狗,在24小时内,霍尔特衍生的平均心率(meanHRHolter)与随后连续的24小时没有显著差异。25只AF犬。方法前瞻性、描述性、多中心研究。同时,前瞻性分析AAD开始后的动态心律失常率和室性心律失常(VAs)。临床相关差异(定义为平均hrholter≥10 bpm)、速率控制成功(定义为平均hrholter≤125 bpm)。计算Bland-Altman分析和类内相关系数(ICC)来比较两个连续的24小时动态心电图记录。VAs百分比差异[(最大日值-最小日值)/最大日值× 100]和记录之间的分级可变性也进行了研究。结果平均hrholter的偏差较小,ICC为0.98(95%可信区间[CI] 0.95-0.99),连续两次24小时Holter记录之间无统计学差异(95% CI[−2.84-2.92],自由度24,p = 0.98)。只有2/25只狗(8%;95% CI[2%-25%])有临床显著差异,而1/25 (4%;95% CI[0%-20%])的犬在连续记录之间的成功率控制成功率表现出不同的分类。VAs百分比差异为52%,其中7/25 (28%;95% CI [14%-47%]), VAs评分差异≥2。结论及临床意义房颤犬接受AAD时的每日心率变异性较低,提示单次24小时动态心电图记录足以评估心率控制情况。当评估伴有房颤的犬的VAs时,每日变异性可能是一个重要的考虑因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
4.50
自引率
11.50%
发文量
243
审稿时长
22 weeks
期刊介绍: The mission of the Journal of Veterinary Internal Medicine is to advance veterinary medical knowledge and improve the lives of animals by publication of authoritative scientific articles of animal diseases.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信