Rapid detection of organophosphorus pesticide monocrotophos by pore size-regulated amplified fluorescence “turn-on” response of Zr-MOF

IF 5.7 2区化学 Q1 CHEMISTRY, ANALYTICAL

Analytica Chimica Acta Pub Date : 2025-03-07 DOI:10.1016/j.aca.2025.343915

Xinying Gong , Yulu Tian , Yuanjun Tong , Yibin Yuan , Shiyu Peng , Dongmei Wang , Hongqun Tao , Qinwen Tan , Zhengjun Gong

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引用次数: 0

Abstract

Background

Organophosphorus pesticides pose a severe threat to human health even at trace levels in the environment, owing to their high persistence and neurotoxic effects. Rapid detection methods based on luminescent metal organic frameworks (LMOFs) have great advantages in environmental applications, attributing to their unique luminescence characteristics, structural flexibility, high porosity, and tunable synthesis. Therefore, an effective strategy for adjusting pore size in LMOFs is essential to enhance the sensitivity and selectivity of fluorescence recognition.

Results

In this study, a fluorescence probe NH₂-UiO-66@cur was synthesized, where curcumin was utilized to modulate the pore size of NH₂-UiO-66, resulting in a fluorescence “turn-on” response for the rapid detection of monocrotophos (MCP). The incorporation of curcumin increased the average pore size of NH₂-UiO-66 from 2.01 to 3.61 nm, thereby facilitating the mass transfer of MCP in NH₂-UiO-66@cur. Additionally, the coordinating of MCP with the zirconium node effectively block the ligand-to-metal charge transfer (LMCT) process, significantly improving sensitivity with an ultra-low detection limit of 0.41 μg L⁻¹ for MCP. The NH₂-UiO-66@cur sensor exhibited excellent selectivity for MCP compared to other organosphosphorus compounds, as well as robust interference resistance. In practical applications, the fluorescence probe showed stable and accurate detection potential, with spiking recoveries ranging from 84.2 % to 105 % in environmental water samples.

Significance

This work provides a novel strategy for tailoring the pore size for a MOF sensor platform, which notably enhances the mass transfer and fluorescence emission intensity by blocking LMCT effect. As a result, it improves the detection sensitivity and selectivity on trace organophosphate pollutants in the environment samples, addressing critical concerns in environmental monitoring.

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来源期刊

Analytica Chimica Acta 化学-分析化学

CiteScore

10.40

自引率

6.50%

发文量

1081

审稿时长

38 days

期刊介绍： Analytica Chimica Acta has an open access mirror journal Analytica Chimica Acta: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review. Analytica Chimica Acta provides a forum for the rapid publication of original research, and critical, comprehensive reviews dealing with all aspects of fundamental and applied modern analytical chemistry. The journal welcomes the submission of research papers which report studies concerning the development of new and significant analytical methodologies. In determining the suitability of submitted articles for publication, particular scrutiny will be placed on the degree of novelty and impact of the research and the extent to which it adds to the existing body of knowledge in analytical chemistry.