Management of dropped head syndrome: a systematic review and single-arm meta-analysis.

IF 2.5 3区 医学 Q2 CLINICAL NEUROLOGY
Matheus Felipe Henriques Brandão, Ocílio Ribeiro Gonçalves, Gabriel de Almeida Monteiro, Vitor Ribeiro Gonçalves, João Vitor Andrade Fernandes, Thiago Gomes Martins
{"title":"Management of dropped head syndrome: a systematic review and single-arm meta-analysis.","authors":"Matheus Felipe Henriques Brandão, Ocílio Ribeiro Gonçalves, Gabriel de Almeida Monteiro, Vitor Ribeiro Gonçalves, João Vitor Andrade Fernandes, Thiago Gomes Martins","doi":"10.1007/s10143-025-03443-y","DOIUrl":null,"url":null,"abstract":"<p><p>Dropped Head Syndrome (DHS) is a rare condition marked by severe neck extensor muscle weakness, leading to a chin-on-chest deformity caused by pathological kyphosis. This study aims to evaluate the efficacy of conservative versus surgical treatments for DHS. A systematic search of PubMed, Embase, and ScienceDirect was conducted for studies on DHS treatments. Outcomes included total/partial improvement, success, and failure rates. Statistical analyses were performed using R software and the \"meta\" package. We identified 1,252 articles, with 19 studies and 472 patients included. Of these, 134 (28.4%) underwent surgery and 338 (71.6%) received conservative treatment. Partial improvement after conservative treatment was 59% (95% CI 32.76-83.03%; I² = 78%), with total improvement at 4.45% (95% CI 0.01-13.21%; I² = 84%). Success rates were 6.73% (95% CI 0.74-16.16%; I² = 82%), and failure was 100% (95% CI 99.28-100%; I² = 78%). For surgical treatment, total improvement was 100% (95% CI 99.57-100%; I² = 18%), and success was also 100% (95% CI 98.37-100%; I² = 0%), with low heterogeneity. Only two surgical patients failed (95% CI 0.00-1.63%; I² = 0%). Conservative treatment was ineffective in achieving functional recovery and horizontal gaze. Surgical treatment is the preferred option for treating DHS and should be considered a disease-modifying therapy.</p>","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"48 1","pages":"284"},"PeriodicalIF":2.5000,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neurosurgical Review","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s10143-025-03443-y","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Dropped Head Syndrome (DHS) is a rare condition marked by severe neck extensor muscle weakness, leading to a chin-on-chest deformity caused by pathological kyphosis. This study aims to evaluate the efficacy of conservative versus surgical treatments for DHS. A systematic search of PubMed, Embase, and ScienceDirect was conducted for studies on DHS treatments. Outcomes included total/partial improvement, success, and failure rates. Statistical analyses were performed using R software and the "meta" package. We identified 1,252 articles, with 19 studies and 472 patients included. Of these, 134 (28.4%) underwent surgery and 338 (71.6%) received conservative treatment. Partial improvement after conservative treatment was 59% (95% CI 32.76-83.03%; I² = 78%), with total improvement at 4.45% (95% CI 0.01-13.21%; I² = 84%). Success rates were 6.73% (95% CI 0.74-16.16%; I² = 82%), and failure was 100% (95% CI 99.28-100%; I² = 78%). For surgical treatment, total improvement was 100% (95% CI 99.57-100%; I² = 18%), and success was also 100% (95% CI 98.37-100%; I² = 0%), with low heterogeneity. Only two surgical patients failed (95% CI 0.00-1.63%; I² = 0%). Conservative treatment was ineffective in achieving functional recovery and horizontal gaze. Surgical treatment is the preferred option for treating DHS and should be considered a disease-modifying therapy.

掉头综合征的治疗:系统回顾和单臂荟萃分析。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Neurosurgical Review
Neurosurgical Review 医学-临床神经学
CiteScore
5.60
自引率
7.10%
发文量
191
审稿时长
6-12 weeks
期刊介绍: The goal of Neurosurgical Review is to provide a forum for comprehensive reviews on current issues in neurosurgery. Each issue contains up to three reviews, reflecting all important aspects of one topic (a disease or a surgical approach). Comments by a panel of experts within the same issue complete the topic. By providing comprehensive coverage of one topic per issue, Neurosurgical Review combines the topicality of professional journals with the indepth treatment of a monograph. Original papers of high quality are also welcome.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信