Comprehensive Analysis of the Biomechanical Research of Pelvic Organ Prolapse: A Scientometric Approach.

Abstract

Background: Pelvic organ prolapse (POP) has become a significant public health issue, with its prevalence increasing proportionally with age. Despite the considerable number of biomechanical studies reported on POP, there remains a lack of a systematic approach to summarize and synthesize all existing research.

Methods: The Web of Science Core Collection (WoSCC) database was used as the data source to select literature published from 2003 to 2023 related to biomechanical research of POP. We employed various visualization software to generate scientific knowledge maps, facilitating data analysis and visual representation.

Results: This study included 292 publications, comprising 252 research articles (86.3%) and 40 review articles (13.7%). The United States has emerged as a leading nation in terms of productivity, with the University of Porto making significant contributions. Robust partnerships are maintained by all countries and institutions involved. Moali PA stands out as the most prolific author, while Deprest J exhibits exemplary levels of collaboration. Notably, the journal Int Urogynecol J has the highest publication rate and citation frequency, making a significant contribution and demonstrating considerable academic influence in the field. Keyword and cluster analysis reveal that key research areas include validating finite element (FE) models of pelvic floor structures, studying interactions among pelvic support systems, evaluating the impact of vaginal delivery, assessing the effects of various mesh or 3D-printed materials on POP repair, remodeling vaginal connective tissue in POP patients, and biomechanical performance evaluations of pelvic floor tissues. Future research will likely focus on the development of personalized and regenerative treatment strategies. Moreover, advancements in machine learning, various regenerative medicine approaches, and multimodal large-scale FE modeling offer promising insights for development.

Conclusion: This study presents a comprehensive analysis of the knowledge system and research directions of the biomechanics of POP, providing valuable guidance for future research endeavors.