Natalie Van Ochten, Eric W Rudofker, William K Cornwell
{"title":"Altitude Adversities: Is It Safe for People with Cardiovascular Disease to Travel to Moderate-High Altitude?","authors":"Natalie Van Ochten, Eric W Rudofker, William K Cornwell","doi":"10.1089/ham.2024.0097","DOIUrl":null,"url":null,"abstract":"<p><p>Van Ochten, Natalie, Eric W. Rudofker, and William K. Cornwell. Altitude adversities: is it safe for people with cardiovascular disease to travel to moderate-high altitude? <i>High Alt Med Biol.</i> 00:00-00, 2025.-The risk of acute cardiac events increases following acute exposure to hypoxia associated with travel to moderate-high altitudes. Herein, we present seven illustrative cases among lowlanders who presented to our center (1,609 m, equivalent fraction of inspired oxygen [F<sub>I</sub>O<sub>2</sub>] ∼0.17) with acute cardiac emergencies during travel to moderate-high altitude. We also provide a concise, yet comprehensive, review of the relevant physiology pertaining to the impact of acute hypoxia on cardiovascular physiology and mechanisms by which altitude exposure may increase the risk of adverse events.</p>","PeriodicalId":12975,"journal":{"name":"High altitude medicine & biology","volume":" ","pages":""},"PeriodicalIF":1.6000,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"High altitude medicine & biology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1089/ham.2024.0097","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"BIOPHYSICS","Score":null,"Total":0}
引用次数: 0
Abstract
Van Ochten, Natalie, Eric W. Rudofker, and William K. Cornwell. Altitude adversities: is it safe for people with cardiovascular disease to travel to moderate-high altitude? High Alt Med Biol. 00:00-00, 2025.-The risk of acute cardiac events increases following acute exposure to hypoxia associated with travel to moderate-high altitudes. Herein, we present seven illustrative cases among lowlanders who presented to our center (1,609 m, equivalent fraction of inspired oxygen [FIO2] ∼0.17) with acute cardiac emergencies during travel to moderate-high altitude. We also provide a concise, yet comprehensive, review of the relevant physiology pertaining to the impact of acute hypoxia on cardiovascular physiology and mechanisms by which altitude exposure may increase the risk of adverse events.
期刊介绍：
High Altitude Medicine & Biology is the only peer-reviewed journal covering the medical and biological issues that impact human life at high altitudes. The Journal delivers critical findings on the impact of high altitude on lung and heart disease, appetite and weight loss, pulmonary and cerebral edema, hypertension, dehydration, infertility, and other diseases. It covers the full spectrum of high altitude life sciences from pathology to human and animal ecology.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
