Incidence and survival of patients with melanoma in Colombia

IF 2.4 3区医学 Q3 ONCOLOGY

Cancer Epidemiology Pub Date : 2025-03-06 DOI:10.1016/j.canep.2025.102784

Henry Oliveros , Juliana Usta Stavoli , Nadia Juliana Proaños , Julio Roberto Amador , Luis Felipe Reyes

{"title":"Incidence and survival of patients with melanoma in Colombia","authors":"Henry Oliveros , Juliana Usta Stavoli , Nadia Juliana Proaños , Julio Roberto Amador , Luis Felipe Reyes","doi":"10.1016/j.canep.2025.102784","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>Melanoma accounts for less than 2 % of all skin cancers but exhibits highly aggressive behaviour, rapidly leading to metastasis. Various individual and environmental risk factors are associated with its occurrence.</div></div><div><h3>Methods</h3><div>A cohort study was conducted using data from the Integrated Social Protection Information System (SISPRO) of the Colombian Ministry of Health. Patients with newly diagnosed melanoma in 2019 were included. Demographic, clinical, and mortality characteristics were analysed, and crude and age- and sex-adjusted incidence rates were calculated. The association between the altitude of populations and melanoma rates was evaluated using Pearson’s correlation coefficient and an analysis of variance. The Fine and Gray model was used to estimate survival.</div></div><div><h3>Results</h3><div>In 2019, 5255 new cases of melanoma were reported in the health insurance system. The crude incidence rate was 22 cases per 100,000 inhabitants, and the age-adjusted incidence rate was 21. The overall three-year mortality rate was 18.8 %, with melanoma-attributable mortality at 7 %. As expected, the mortality rate was higher in patients with invasive melanoma, COPD, and among men. Melanoma rates were positively correlated with greater exposure to UV radiation, determined by the altitude of the municipalities.</div></div><div><h3>Conclusion</h3><div>Colombia has high melanoma incidence rates, with significant regional variations. UV radiation exposure and altitude are key factors.</div></div>","PeriodicalId":56322,"journal":{"name":"Cancer Epidemiology","volume":"96 ","pages":"Article 102784"},"PeriodicalIF":2.4000,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cancer Epidemiology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S187778212500044X","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ONCOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Background

Melanoma accounts for less than 2 % of all skin cancers but exhibits highly aggressive behaviour, rapidly leading to metastasis. Various individual and environmental risk factors are associated with its occurrence.

Methods

A cohort study was conducted using data from the Integrated Social Protection Information System (SISPRO) of the Colombian Ministry of Health. Patients with newly diagnosed melanoma in 2019 were included. Demographic, clinical, and mortality characteristics were analysed, and crude and age- and sex-adjusted incidence rates were calculated. The association between the altitude of populations and melanoma rates was evaluated using Pearson’s correlation coefficient and an analysis of variance. The Fine and Gray model was used to estimate survival.

Results

In 2019, 5255 new cases of melanoma were reported in the health insurance system. The crude incidence rate was 22 cases per 100,000 inhabitants, and the age-adjusted incidence rate was 21. The overall three-year mortality rate was 18.8 %, with melanoma-attributable mortality at 7 %. As expected, the mortality rate was higher in patients with invasive melanoma, COPD, and among men. Melanoma rates were positively correlated with greater exposure to UV radiation, determined by the altitude of the municipalities.

Conclusion

Colombia has high melanoma incidence rates, with significant regional variations. UV radiation exposure and altitude are key factors.

查看原文本刊更多论文

求助全文

约1分钟内获得全文求助全文

来源期刊

Cancer Epidemiology 医学-肿瘤学

CiteScore

4.50

自引率

3.80%

发文量

200

审稿时长

39 days

期刊介绍： Cancer Epidemiology is dedicated to increasing understanding about cancer causes, prevention and control. The scope of the journal embraces all aspects of cancer epidemiology including: • Descriptive epidemiology • Studies of risk factors for disease initiation, development and prognosis • Screening and early detection • Prevention and control • Methodological issues The journal publishes original research articles (full length and short reports), systematic reviews and meta-analyses, editorials, commentaries and letters to the editor commenting on previously published research.