An overview of hydrophobic deep eutectic solvents driven liquid-phase extraction: Applications and prospects

IF 3.8 2区化学 Q1 BIOCHEMICAL RESEARCH METHODS

Journal of Chromatography A Pub Date : 2025-02-26 DOI:10.1016/j.chroma.2025.465824

Xinxin Zheng , Fan Yin , Gang Gong , Xinger Zhang , Sile He , Weiyang Tang , Xiao-Hong Wei

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引用次数: 0

Abstract

Deep eutectic solvents (DESs) are a type of emerging green solvent. They are simple to prepare, cost-effective, highly atom-efficient, exhibit extremely low toxicity, and are biodegradable. Since their discovery, DESs have attracted significant interest from the scientific community across various fields. In recent years, these solvents have been extensively studied by researchers as extraction media. Hydrophobic deep eutectic solvents (hDESs) first appeared in the literature in 2015 and represent a group of DESs that meet the requirements of green chemistry. hDESs have great potential in the fields of separation and extraction and are considered effective alternatives to replace hydrophilic DESs and other hydrophobic organic solvents for the extraction of lipophilic natural products. This review summarizes pioneering and innovative work on hDESs, including the latest research progress regarding their applications, extraction techniques, and recycling methods. It also highlights issues that need to be addressed in the future. The results of hDESs in natural product extraction and the extraction of other compounds have revealed their significant potential as alternative green solvents in industrial separation processes.

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来源期刊

Journal of Chromatography A 化学-分析化学

CiteScore

7.90

自引率

14.60%

发文量

742

审稿时长

45 days

期刊介绍： The Journal of Chromatography A provides a forum for the publication of original research and critical reviews on all aspects of fundamental and applied separation science. The scope of the journal includes chromatography and related techniques, electromigration techniques (e.g. electrophoresis, electrochromatography), hyphenated and other multi-dimensional techniques, sample preparation, and detection methods such as mass spectrometry. Contributions consist mainly of research papers dealing with the theory of separation methods, instrumental developments and analytical and preparative applications of general interest.