A novel surgical technique for cranial cruciate ligament repair in dogs using autologous lateral digital extensor muscle tendon graft combined with platelet-rich plasma: A preliminary experimental study.

IF 1.7 Q2 AGRICULTURE, DAIRY & ANIMAL SCIENCE
Veterinary World Pub Date : 2025-01-01 Epub Date: 2025-01-30 DOI:10.14202/vetworld.2025.210-219
Mousa H Daradka, Mays A Malkawi, Zuhair Banni Ismail, Hanan M Hammouri, Mahmoud A Abu-Abeeleh, Saba A Rihani
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引用次数: 0

Abstract

Background and aim: Cranial cruciate ligament (CrCL) injuries are a prevalent orthopedic issue in dogs, typically managed through surgical interventions such as tibial plateau leveling osteotomy and tibial tuberosity advancement. However, these techniques have limitations, including high costs and extended recovery periods. This study introduces an innovative CrCL repair method employing an autologous lateral digital extensor muscle tendon graft and evaluates the effects of platelet-rich plasma (PRP) on tissue healing.

Materials and methods: Twenty-four healthy, male, local-breed dogs were divided into two groups. Group A underwent the surgical procedure without PRP, while Group B received intra-articular PRP during surgery. Outcomes were evaluated through clinical assessments of lameness, post-operative complications, and histological analysis over 10, 20, 30, and 40 days.

Results: The PRP-treated group demonstrated statistically significant improvements in post-operative complication scores (p = 0.0025) and histological outcomes (p = 0.0002). However, graft maturation was unaffected by PRP treatment but improved over time (p = 0.0013). PRP-treated dogs exhibited faster recovery and enhanced tissue regeneration, with reduced inflammation and improved graft-bone attachment.

Conclusion: This novel surgical approach demonstrates significant potential for improving outcomes in CrCL repair by combining autologous tendon grafting with PRP. The technique offers reduced complications and enhanced healing, providing a promising alternative to traditional methods. Further studies are recommended to validate its efficacy in clinical settings.

自体指外侧伸肌肌腱联合富血小板血浆修复犬颅十字韧带的新手术技术:初步实验研究。
背景和目的:颅十字韧带(CrCL)损伤是犬骨科常见的问题,通常通过手术干预治疗,如胫骨平台水平截骨和胫骨结节推进。然而,这些技术有其局限性,包括高成本和较长的回收周期。本研究介绍了一种采用自体外侧指伸肌肌腱移植修复CrCL的创新方法,并评估了富血小板血浆(PRP)对组织愈合的影响。材料与方法:24只健康雄性地方犬分为两组。A组手术过程中不进行PRP治疗,B组手术过程中进行关节内PRP治疗。通过10、20、30和40天的跛行临床评估、术后并发症和组织学分析来评估结果。结果:prp治疗组术后并发症评分(p = 0.0025)和组织学结果(p = 0.0002)均有统计学意义的改善。然而,移植物成熟不受PRP处理的影响,但随着时间的推移而改善(p = 0.0013)。prp治疗的狗表现出更快的恢复和增强的组织再生,炎症减少,移植物骨附着改善。结论:采用自体肌腱移植联合PRP修复CrCL,这种新颖的手术方式具有显著改善CrCL修复效果的潜力。这项技术减少了并发症,增强了愈合,为传统方法提供了一个有希望的替代方案。建议进一步研究以验证其在临床环境中的有效性。
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来源期刊
Veterinary World
Veterinary World Multiple-
CiteScore
3.60
自引率
12.50%
发文量
317
审稿时长
16 weeks
期刊介绍: Veterinary World publishes high quality papers focusing on Veterinary and Animal Science. The fields of study are bacteriology, parasitology, pathology, virology, immunology, mycology, public health, biotechnology, meat science, fish diseases, nutrition, gynecology, genetics, wildlife, laboratory animals, animal models of human infections, prion diseases and epidemiology. Studies on zoonotic and emerging infections are highly appreciated. Review articles are highly appreciated. All articles published by Veterinary World are made freely and permanently accessible online. All articles to Veterinary World are posted online immediately as they are ready for publication.
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