The Association of Peripheral Refraction and Relative Peripheral Refraction with Astigmatism in Shanghai Schoolchildren's Myopia: A Cross-Sectional Study.

IF 1.7 4区医学 Q3 OPHTHALMOLOGY

Ophthalmic epidemiology Pub Date : 2025-03-04 DOI:10.1080/09286586.2025.2459755

Huiyu Chen, Meng Chen, Junjie Zhang, Jun Chen, Yan Xu

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引用次数: 0

Abstract

Purpose: Currently, no relevant studies have reported a relationship between astigmatism and peripheral refraction (PR). We aimed to describe the association between PR and relative peripheral refraction (RPR) with astigmatism in Chinese children with mild to moderate myopia, and to provide new insights into the influence of astigmatism.

Methods: Three-hundred-and-seven children (6-14 years old) from Shanghai were included in this study. The PR and RPR were measured using multispectral refraction topography (MRT). Cycloplegic refraction was measured using an autorefractor (KR-8900, Topcon), whereas axial length and ocular biological parameters were measured using Zeiss IOLMaster 700. Only data from the right eye were analyzed. Multivariate linear regression was used to explore the relationship between cylinder power and MRT parameters.

Results: Overall, the median spherical equivalent was -1.50 D (interquartile range, IQR: -2.25, -0.88), showing an apparent trend of hyperopic defocus from the macula to the peripheral retina. Astigmatism was correlated with PR rather than RPR especially at eccentrically inferior and within a 45° radius of the retina (coefficients 0.12-0.18, p < 0.05). Multivariate linear regression analysis demonstrated that the effect of astigmatism on PR tended to increase with greater lens thickness.

Conclusions: Astigmatism may be a risk factor for myopia due to its impact on peripheral refraction as opposed to relative peripheral refraction. In this cross-sectional study, we also found evidence supporting the association between peripheral hyperopia and myopia.

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来源期刊

Ophthalmic epidemiology 医学-眼科学

CiteScore

3.70

自引率

5.60%

发文量

审稿时长

6-12 weeks

期刊介绍： Ophthalmic Epidemiology is dedicated to the publication of original research into eye and vision health in the fields of epidemiology, public health and the prevention of blindness. Ophthalmic Epidemiology publishes editorials, original research reports, systematic reviews and meta-analysis articles, brief communications and letters to the editor on all subjects related to ophthalmic epidemiology. A broad range of topics is suitable, such as: evaluating the risk of ocular diseases, general and specific study designs, screening program implementation and evaluation, eye health care access, delivery and outcomes, therapeutic efficacy or effectiveness, disease prognosis and quality of life, cost-benefit analysis, biostatistical theory and risk factor analysis. We are looking to expand our engagement with reports of international interest, including those regarding problems affecting developing countries, although reports from all over the world potentially are suitable. Clinical case reports, small case series (not enough for a cohort analysis) articles and animal research reports are not appropriate for this journal.