Efficacy of Therapeutic Ultrasound Added to Complex Decongestive Therapy in Breast Cancer-Related Lymphedema.

IF 1.9 4区 医学 Q3 MEDICINE, RESEARCH & EXPERIMENTAL
Lymphatic research and biology Pub Date : 2025-08-01 Epub Date: 2025-03-05 DOI:10.1089/lrb.2023.0019
Mihriban Cağlı, Burcu Duyur Çakıt, Secil Pervane
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引用次数: 0

Abstract

Objective: To determine the efficacy of therapeutic ultrasound (TUS) added to complex decongestive therapy (CDT) in patients with breast cancer-related lymphedema (BCRL). Materials and Methods: Thirty female volunteer patients who developed stage 2-3 BCRL were included in the study. The patients were randomly assigned to one of two groups: standard treatment with CDT alone and CDT + TUS. Before the study, both groups were given a training and home program consisting of remedial exercises and skin care. All patients received 15 sessions of treatment over 3 weeks. Circumferential and ultrasonographic (USG) measurements of all patients were performed before and after treatment. Treatment efficacy was evaluated based on extremity volume and soft tissue thickness. Results: The demographic data and volume measurements of the patients were similar at the beginning of treatment. There was a statistically significant decrease in the affected extremity in both groups in posttreatment circumferential measurements. However, the reductions in volume difference and volume difference percentage were significantly higher in the CDT + TUS group (p = 0.001 and p = 0.002, respectively). In the USG measurements, a greater decrease was observed in the soft tissue thickness below the elbow in the CDT + TUS group compared with the CDT alone group (p = 0.003). Conclusion: In the treatment of BCRL, TUS added to CDT resulted in a reduction in lymphedema. We consider that when added to CDT, TUS can increase the efficacy of treatment by reducing lymphedema in stages 2 and 3 lymphedema cases.

超声辅助综合降血治疗乳腺癌相关淋巴水肿的疗效观察。
目的:探讨超声辅助综合减充血治疗(CDT)对乳腺癌相关性淋巴水肿(BCRL)的疗效。材料与方法:30例2-3期BCRL女性志愿者纳入研究。患者被随机分为两组:CDT单独标准治疗和CDT + TUS治疗。在研究之前,两组人都接受了包括补救练习和皮肤护理在内的培训和家庭计划。所有患者在3周内接受了15次治疗。所有患者在治疗前和治疗后均行周向和超声(USG)测量。根据肢体体积和软组织厚度评估治疗效果。结果:患者在治疗初期的人口学数据和体积测量相似。治疗后两组患者患肢的周向测量均有统计学意义的降低。然而,CDT + TUS组的体积差和体积差百分比的减少明显更高(p = 0.001和p = 0.002)。在USG测量中,与单独CDT组相比,CDT + TUS组肘部以下软组织厚度下降更大(p = 0.003)。结论:在BCRL治疗中,加入CDT的TUS可减少淋巴水肿。我们认为,当加入CDT时,TUS可以通过减少2期和3期淋巴水肿病例的淋巴水肿来提高治疗效果。
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来源期刊
Lymphatic research and biology
Lymphatic research and biology Medicine-Cardiology and Cardiovascular Medicine
CiteScore
3.10
自引率
7.10%
发文量
85
审稿时长
>12 weeks
期刊介绍: Lymphatic Research and Biology delivers the most current peer-reviewed advances and developments in lymphatic biology and pathology from the world’s leading biomedical investigators. The Journal provides original research from a broad range of investigative disciplines, including genetics, biochemistry and biophysics, cellular and molecular biology, physiology and pharmacology, anatomy, developmental biology, and pathology. Lymphatic Research and Biology coverage includes: -Vasculogenesis and angiogenesis -Genetics of lymphatic disorders -Human lymphatic disease, including lymphatic insufficiency and associated vascular anomalies -Physiology of intestinal fluid and protein balance -Immunosurveillance and immune cell trafficking -Tumor biology and metastasis -Pharmacology -Lymphatic imaging -Endothelial and smooth muscle cell biology -Inflammation, infection, and autoimmune disease
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