Clinical Investigations and Therapeutic Perspectives on Metabolic Syndrome following Kidney Transplantation.

IF 2.3 4区医学 Q2 PERIPHERAL VASCULAR DISEASE

Kidney & blood pressure research Pub Date : 2025-01-01 Epub Date: 2025-03-04 DOI:10.1159/000545032

Kejing Zhu, Yuji Jin, Weijian Liu, Cheng Wen, Xinrui Zheng, Zhixiong Li, Yunjian Chen, Yulin Niu, Wei Pan, Yong Jiang, Yingji Jin

引用次数: 0

Abstract

Background: Kidney transplantation was an effective method for treating chronic kidney failure via transplanting a healthy kidney from a donor to a patient with the loss of kidney function. However, clinical studies revealed that the posttransplantation status of patients was associated with a substantial aggregation of risk factors contributing to metabolic syndrome.

Summary: This article provided a comprehensive review of the current researches on metabolic syndrome after kidney transplantation, and the latest advances in the interaction between metabolism and immune cells were also covered.

Key messages: Our aim was to identify and intervene high-risk recipients in time and thus improving the prognosis of recipients.

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肾移植后代谢综合征的临床研究及治疗前景。

背景：肾移植是治疗慢性肾衰竭的一种有效方法，方法是将供者的健康肾脏移植给肾功能丧失的患者。然而，临床研究显示，移植后患者的状态与导致代谢综合征的大量危险因素相关。摘要：本文对肾移植后代谢综合征的研究现状进行了综述，并对代谢与免疫细胞相互作用的最新进展进行了综述。关键信息：我们的目的是及时识别和干预高危受体，从而改善受体的预后。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Kidney & blood pressure research 医学-泌尿学与肾脏学

CiteScore

4.80

自引率

3.60%

发文量

审稿时长

6-12 weeks

期刊介绍： This journal comprises both clinical and basic studies at the interface of nephrology, hypertension and cardiovascular research. The topics to be covered include the structural organization and biochemistry of the normal and diseased kidney, the molecular biology of transporters, the physiology and pathophysiology of glomerular filtration and tubular transport, endothelial and vascular smooth muscle cell function and blood pressure control, as well as water, electrolyte and mineral metabolism. Also discussed are the (patho)physiology and (patho) biochemistry of renal hormones, the molecular biology, genetics and clinical course of renal disease and hypertension, the renal elimination, action and clinical use of drugs, as well as dialysis and transplantation. Featuring peer-reviewed original papers, editorials translating basic science into patient-oriented research and disease, in depth reviews, and regular special topic sections, ''Kidney & Blood Pressure Research'' is an important source of information for researchers in nephrology and cardiovascular medicine.