Piloting the better research interactions for every family (BRIEF) researcher intervention to support recruitment for a neonatal clinical trial: parent experience and infant enrollment.

IF 2.4 3区医学 Q2 OBSTETRICS & GYNECOLOGY

Journal of Perinatology Pub Date : 2025-03-04 DOI:10.1038/s41372-025-02245-w

Elliott Mark Weiss, Devan M Duenas, Andrea Kelsh, Megan M Gray, Ellie Oslin, Devinae Mcneil, Sandra E Juul, Stephanie A Kraft

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引用次数: 0

Abstract

Objective: Recruiting for neonatal clinical trials is difficult for families and participation rates are low. We partnered with the DIVI (Darbepoetin plus slow-release IntraVenous Iron) trial for pilot feasibility evaluation of the BRIEF (Better Research Interactions for Every Family) intervention.

Study design: Pre/post design to compare infant data and parent surveys and interviews before and after the BRIEF intervention as well as comparing DIVI enrolled and DIVI not enrolled.

Results: Enrollment rates and parental experiences were similar in pre- and post-BRIEF eras. Most respondents reported positive interactions with researchers. Parents who declined DIVI reported somewhat worse experiences compared to those who enrolled. Interview respondents reported widely variable experiences. The narrow enrollment window emerged as particularly important to parents' recruitment experience.

Conclusions: The BRIEF intervention was well received and is ready for larger scale testing to assess its impact on parental experience and enrollment rates. Future work should address short enrollment windows common in neonatal clinical trials.

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为每个家庭提供更好的研究互动（BRIEF）研究人员干预以支持新生儿临床试验的招募：父母经验和婴儿入组。

目的：新生儿临床试验的家庭招募困难，参与率低。我们与DIVI （Darbepoetin +缓释静脉铁）试验合作，对BRIEF （Better Research Interactions for each Family）干预进行试点可行性评估。研究设计：前后设计，比较BRIEF干预前后的婴儿数据、父母调查和访谈，以及比较DIVI入组和未入组。结果：在brief之前和之后，入学率和父母经历相似。大多数受访者表示与研究人员有积极的互动。拒绝DIVI的父母报告的经历比参加DIVI的父母更糟糕。受访者的经历千差万别。狭小的招生窗口对家长的招生体验尤为重要。结论：BRIEF干预效果良好，并准备进行更大规模的测试，以评估其对家长体验和入学率的影响。未来的工作应该解决新生儿临床试验中常见的短入组窗口问题。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Perinatology 医学-妇产科学

CiteScore

5.40

自引率

6.90%

发文量

284

审稿时长

3-8 weeks

期刊介绍： The Journal of Perinatology provides members of the perinatal/neonatal healthcare team with original information pertinent to improving maternal/fetal and neonatal care. We publish peer-reviewed clinical research articles, state-of-the art reviews, comments, quality improvement reports, and letters to the editor. Articles published in the Journal of Perinatology embrace the full scope of the specialty, including clinical, professional, political, administrative and educational aspects. The Journal also explores legal and ethical issues, neonatal technology and product development. The Journal’s audience includes all those that participate in perinatal/neonatal care, including, but not limited to neonatologists, perinatologists, perinatal epidemiologists, pediatricians and pediatric subspecialists, surgeons, neonatal and perinatal nurses, respiratory therapists, pharmacists, social workers, dieticians, speech and hearing experts, other allied health professionals, as well as subspecialists who participate in patient care including radiologists, laboratory medicine and pathologists.