Achieving low radiation dose and contrast agents dose in coronary CT angiography at 60-kVp ultra-low tube voltage.

IF 2.9 3区 医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Weiling He, Feng Huang, Xi Wu, An Xie, Wenjie Sun, Peng Liu, Rui Hu
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Abstract

Objectives: To explore the feasibility of a one-beat protocol and ultra-low tube voltage of 60 kVp in coronary CT angiography (CCTA).

Methods: This prospective study enrolled 107 patients (body mass index ≤ 26 kg/m2) undergoing CCTA examinations. Specifically, the conventional group (n = 52) underwent 100 kVp scanning with 45 ml iodine contrast agent and 4 ml/s injection rate, and the low-dose group (n = 55) underwent 60 kVp scanning with 28 ml iodine contrast agent and 2.5 ml/s injection rate. The CT value, signal-noise-ratio (SNR), contrast-noise-ratio (CNR) and subjective image quality score of two groups in aorta (AO), right coronary artery (RCA), left anterior descending (LAD) and left circumflex (LCX) are analyzed in this study. Three types of radiation doses [i.e., volume CT dose index (CTDIvol), dose length product (DLP), effective dose (ED)] of two groups are also compared.

Results: The quantitative results indicated that the low-dose group achieved higher CT values, SNR and CNR results of the AO than the conventional group (P values < 0.001). Both groups had similar CT values, SNR and CNR results in RCA, LAD, and LCX (P values > 0.05). A good agreement is noted with respect to subjective image quality scores in both groups, while the Cohen's kappa value is 0.815 in the low-dose group and 0.825 in the conventional group, respectively. In addition, the radiation dose of the low-dose group is significantly lower than the conventional group in terms of CTDIvol, DLP and ED values, and the contrast dose in the low-dose group is also significantly reduced compared to the conventional group (P values < 0.001).

Conclusions: One-beat protocol with an ultra-low tube voltage of 60 kVp could provide improved coronary image quality, reduced radiation dose and reduced iodine contrast dose.

在60 kvp的超低管电压下实现冠状动脉CT血管造影低辐射剂量和造影剂剂量。
目的:探讨冠状动脉CT血管造影(CCTA)单拍方案及超低管电压60kvp的可行性。方法:本前瞻性研究纳入107例(体重指数≤26 kg/m2)行CCTA检查的患者。其中,常规组(n = 52)以45 ml碘造影剂100 kVp扫描,注射速度为4 ml/s;低剂量组(n = 55)以28 ml碘造影剂60 kVp扫描,注射速度为2.5 ml/s。本研究分析两组主动脉(AO)、右冠状动脉(RCA)、左前降支(LAD)和左旋支(LCX)的CT值、信噪比(SNR)、比噪比(CNR)和主观图像质量评分。比较两组的三种辐射剂量[即体积CT剂量指数(CTDIvol)、剂量长度积(DLP)、有效剂量(ED)]。结果:定量结果显示,低剂量组AO的CT值、信噪比和CNR结果均高于常规组(P值0.05)。两组主观图像质量评分一致,低剂量组的Cohen’s kappa值为0.815,常规组为0.825。此外,低剂量组的CTDIvol、DLP、ED值均明显低于常规组,低剂量组的造影剂量也明显低于常规组(P值)。结论:超低管电压60 kVp的单拍方案可改善冠状动脉图像质量,降低辐射剂量,降低碘造影剂剂量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
BMC Medical Imaging
BMC Medical Imaging RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
4.60
自引率
3.70%
发文量
198
审稿时长
27 weeks
期刊介绍: BMC Medical Imaging is an open access journal publishing original peer-reviewed research articles in the development, evaluation, and use of imaging techniques and image processing tools to diagnose and manage disease.
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