SGLT2 inhibitors: Exploring the effects in humans and horses

IF 0.8 4区农林科学 Q3 VETERINARY SCIENCES

Equine Veterinary Education Pub Date : 2024-10-29 DOI:10.1111/eve.14071

T. Sundra, V. Matthews, P. Harris, D. Rendle

引用次数: 0

Abstract

Sodium-glucose cotransporter 2 inhibitors (SGLT2i) are human antidiabetic drugs that are increasingly used in equine practice for the management of hyperinsulinaemia and hyperinsulinaemia-associated laminitis. However, the understanding of SGLT2i use in horses is in its infancy compared to human medicine. This review article aims to briefly examine the literature in both species, highlighting current knowledge gaps, potential similarities in therapeutic outcomes and possible adverse effects.

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SGLT2抑制剂：探索对人类和马的影响

钠-葡萄糖共转运蛋白2抑制剂（SGLT2i）是一种人类降糖药，越来越多地用于马的高胰岛素血症和高胰岛素血症相关的板层炎的治疗。然而，与人类医学相比，对SGLT2i在马中的应用的了解尚处于起步阶段。这篇综述文章旨在简要回顾这两个物种的文献，强调目前的知识差距，治疗结果的潜在相似性和可能的不良反应。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Equine Veterinary Education 农林科学-兽医学

CiteScore

2.40

自引率

22.20%

发文量

132

审稿时长

18-36 weeks

期刊介绍： Equine Veterinary Education (EVE) is the official journal of post-graduate education of both the British Equine Veterinary Association (BEVA) and the American Association of Equine Practitioners (AAEP). Equine Veterinary Education is a monthly, peer-reviewed, subscription-based journal, integrating clinical research papers, review articles and case reports from international sources, covering all aspects of medicine and surgery relating to equids. These papers facilitate the dissemination and implementation of new ideas and techniques relating to clinical veterinary practice, with the ultimate aim of promoting best practice. New developments are placed in perspective, encompassing new concepts and peer commentary. The target audience is veterinarians primarily engaged in the practise of equine medicine and surgery. The educational value of a submitted article is one of the most important criteria that are assessed when deciding whether to accept it for publication. Articles do not necessarily need to contain original or novel information but we welcome submission of this material. The educational value of an article may relate to articles published with it (e.g. a Case Report may not have direct educational value but an associated Clinical Commentary or Review Article published alongside it will enhance the educational value).