{"title":"Prevalence of Undiagnosed Hypertension in Bangladesh: A Systematic Review and Meta-Analysis","authors":"Nourin Sultana, Zeba Afia, Shamsuz Zoha, Md. Parvez Mosharaf, Md. Golam Hossain, Md. Kaderi Kibria","doi":"10.1111/jch.70026","DOIUrl":null,"url":null,"abstract":"<p>Undiagnosed hypertension (UHTN) remains a significant public health concern in Bangladesh, leading to severe complications due to delayed diagnosis and management. This systematic review and meta-analysis examined the prevalence of UHTN among adults aged 18 years and older, using data from studies conducted in Bangladesh and published between 2010 and 2024. A comprehensive search of major databases yielded 1028 records, from which nine relevant studies, encompassing a total of 28949 participants, were selected and evaluated for quality using the Newcastle–Ottawa Scale, providing valuable insights into the prevalence of UHTN within the Bangladeshi population. The pooled prevalence of UHTN was 11% (95% CI: 6%–19%) based on a random-effects model, with substantial heterogeneity (<i>I</i><sup>2</sup> = 99.5%, <i>p</i> < 0.0001). Subgroup analyses revealed higher prevalence in rural areas (13%; 95% CI: 4%–35%) compared to urban areas (12%; 95% CI: 1%–54%) and elevated occupational risk among bankers (17%; 95% CI: 0%–94%). While funnel plot asymmetry was noted, Egger's test (<i>p</i> = 0.3113) indicated no significant publication bias. Sensitivity analyses, including Leave-One-Out Analysis, affirmed the robustness of the pooled estimate. The findings underscore notable geographic, occupational, and sociodemographic disparities in UHTN prevalence, highlighting the need for nationwide screening programs and targeted community awareness campaigns, particularly in underserved rural areas. Further research is imperative to explore causal factors and inform effective prevention and management strategies.</p>","PeriodicalId":50237,"journal":{"name":"Journal of Clinical Hypertension","volume":"27 3","pages":""},"PeriodicalIF":2.7000,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jch.70026","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Clinical Hypertension","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/jch.70026","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PERIPHERAL VASCULAR DISEASE","Score":null,"Total":0}
引用次数: 0
Abstract
Undiagnosed hypertension (UHTN) remains a significant public health concern in Bangladesh, leading to severe complications due to delayed diagnosis and management. This systematic review and meta-analysis examined the prevalence of UHTN among adults aged 18 years and older, using data from studies conducted in Bangladesh and published between 2010 and 2024. A comprehensive search of major databases yielded 1028 records, from which nine relevant studies, encompassing a total of 28949 participants, were selected and evaluated for quality using the Newcastle–Ottawa Scale, providing valuable insights into the prevalence of UHTN within the Bangladeshi population. The pooled prevalence of UHTN was 11% (95% CI: 6%–19%) based on a random-effects model, with substantial heterogeneity (I2 = 99.5%, p < 0.0001). Subgroup analyses revealed higher prevalence in rural areas (13%; 95% CI: 4%–35%) compared to urban areas (12%; 95% CI: 1%–54%) and elevated occupational risk among bankers (17%; 95% CI: 0%–94%). While funnel plot asymmetry was noted, Egger's test (p = 0.3113) indicated no significant publication bias. Sensitivity analyses, including Leave-One-Out Analysis, affirmed the robustness of the pooled estimate. The findings underscore notable geographic, occupational, and sociodemographic disparities in UHTN prevalence, highlighting the need for nationwide screening programs and targeted community awareness campaigns, particularly in underserved rural areas. Further research is imperative to explore causal factors and inform effective prevention and management strategies.
期刊介绍:
The Journal of Clinical Hypertension is a peer-reviewed, monthly publication that serves internists, cardiologists, nephrologists, endocrinologists, hypertension specialists, primary care practitioners, pharmacists and all professionals interested in hypertension by providing objective, up-to-date information and practical recommendations on the full range of clinical aspects of hypertension. Commentaries and columns by experts in the field provide further insights into our original research articles as well as on major articles published elsewhere. Major guidelines for the management of hypertension are also an important feature of the Journal. Through its partnership with the World Hypertension League, JCH will include a new focus on hypertension and public health, including major policy issues, that features research and reviews related to disease characteristics and management at the population level.