The Relations Among Anxiety, Movie-Watching, and in-Scanner Motion

Abstract

Movie-watching fMRI has emerged as a theoretically viable platform for studying neurobiological substrates of affective states and emotional disorders such as pathological anxiety. However, using anxiety-inducing movie clips to probe relevant states impacted by psychopathology could risk exacerbating in-scanner movement, decreasing signal quality/quantity and thus statistical power. This could be especially problematic in target populations such as children who typically move more in the scanner. Consequently, we assessed: (1) the extent to which an anxiety-inducing movie clip altered in-scanner data quality (movement, censoring, and DVARS) in a pediatric sample with and without anxiety disorders (n = 78); and (2) investigated interactions between anxiety symptoms and movie-attenuated motion in a highly powered, transdiagnostic pediatric sample (n = 2058). Our results suggest anxiogenic movie-watching in fact reduces in-scanner movement compared to resting-state, increasing the quantity/quality of data. In one measure, pathological anxiety appeared to impact movie-attenuated motion, but the effect was small. Given potential boosts to data quality, future developmental neuroimaging studies of anxiety may benefit from the use of movie paradigms.